Cytomegalovirus Pathogenesis in Transplantation
Cytomegalovirus (CMV) infection is an important cause of morbidity and mortality in the immunocompromised; however, even within this group of patients, infection with CMV is not synonymous with disease. A number of factors affect the pathogenicity of the virus. An understanding of the mechanisms by...
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| Format: | Article |
| Language: | English |
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Wiley
1993-01-01
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| Series: | Canadian Journal of Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/1993/319621 |
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| _version_ | 1832556872403517440 |
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| author | Jane E Grundy |
| author_facet | Jane E Grundy |
| author_sort | Jane E Grundy |
| collection | DOAJ |
| description | Cytomegalovirus (CMV) infection is an important cause of morbidity and mortality in the immunocompromised;
however, even within this group of patients, infection with CMV is not synonymous with
disease. A number of factors affect the pathogenicity of the virus. An understanding of the mechanisms by
which CMV causes disease at different sites in the body, and of how U1at might vary with different patient
groups, is essential to the design of stategies for the prevention and treatment of disease. This review
discusses the factors which affect the occurrence and type of CMV disease in different patient populations,
and considers some of the underlying mechanisms which might contribute to pathology. |
| format | Article |
| id | doaj-art-2dce75d20be14682b4685901e3053b00 |
| institution | Kabale University |
| issn | 1180-2332 |
| language | English |
| publishDate | 1993-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases |
| spelling | doaj-art-2dce75d20be14682b4685901e3053b002025-02-03T05:44:11ZengWileyCanadian Journal of Infectious Diseases1180-23321993-01-014Suppl C111710.1155/1993/319621Cytomegalovirus Pathogenesis in TransplantationJane E GrundyCytomegalovirus (CMV) infection is an important cause of morbidity and mortality in the immunocompromised; however, even within this group of patients, infection with CMV is not synonymous with disease. A number of factors affect the pathogenicity of the virus. An understanding of the mechanisms by which CMV causes disease at different sites in the body, and of how U1at might vary with different patient groups, is essential to the design of stategies for the prevention and treatment of disease. This review discusses the factors which affect the occurrence and type of CMV disease in different patient populations, and considers some of the underlying mechanisms which might contribute to pathology.http://dx.doi.org/10.1155/1993/319621 |
| spellingShingle | Jane E Grundy Cytomegalovirus Pathogenesis in Transplantation Canadian Journal of Infectious Diseases |
| title | Cytomegalovirus Pathogenesis in Transplantation |
| title_full | Cytomegalovirus Pathogenesis in Transplantation |
| title_fullStr | Cytomegalovirus Pathogenesis in Transplantation |
| title_full_unstemmed | Cytomegalovirus Pathogenesis in Transplantation |
| title_short | Cytomegalovirus Pathogenesis in Transplantation |
| title_sort | cytomegalovirus pathogenesis in transplantation |
| url | http://dx.doi.org/10.1155/1993/319621 |
| work_keys_str_mv | AT janeegrundy cytomegaloviruspathogenesisintransplantation |