Metalloproteinases and their Inhibitors under the Course of Immunostimulation by CPG-ODN and Specific Antigen Inhalation in Equine Asthma
Objectives. Inhalation of immunostimulatory bacterial DNA segments (cytosine-phosphate-guanosine-oligodeoxynucleotides, CpG-ODN) normalizes clinical and cytologic parameters in severe equine asthma. We hypothesized that CpG-ODN inhalation also reduces the misbalance of elastinolytic activity in asth...
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Main Authors: | Ann Kristin Barton, Tarek Shety, John Klier, Sabine Geis, Ralf Einspanier, Heidrun Gehlen |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2019/7845623 |
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