Fungal Stress Responses and the Importance of GPCRs
G-protein-coupled receptors (GPCRs) play a crucial role in the gene regulation of processes related to the response to different types of stress in fungi. These receptors act as sensors of extracellular signals and transmit the information to the interior of the cell through G-proteins. In the prese...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-03-01
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| Series: | Journal of Fungi |
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| Online Access: | https://www.mdpi.com/2309-608X/11/3/213 |
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| author | Daniela Lara-Martínez Fabiola Estefania Tristán-Flores Juan Antonio Cervantes-Montelongo Guillermo Antonio Silva-Martínez |
| author_facet | Daniela Lara-Martínez Fabiola Estefania Tristán-Flores Juan Antonio Cervantes-Montelongo Guillermo Antonio Silva-Martínez |
| author_sort | Daniela Lara-Martínez |
| collection | DOAJ |
| description | G-protein-coupled receptors (GPCRs) play a crucial role in the gene regulation of processes related to the response to different types of stress in fungi. These receptors act as sensors of extracellular signals and transmit the information to the interior of the cell through G-proteins. In the presence of different and specific types of stresses, GPCRs activate signaling cascades that culminate in the activation of transcription factors, which regulate the expression of genes associated with the stress response, including those induced by changes in environmental pH. GPCR-mediated gene regulation allows fungi to adapt to adverse conditions such as osmotic, thermal, oxidative, or nutritional stress, as well as fluctuations in environmental pH. This review focuses on the understanding of how GPCRs modulate the stress response in fungi and their crucial role in advancing our knowledge of the physiology and adaptability of these microorganisms in their changing environment. |
| format | Article |
| id | doaj-art-2d9f0b31285745ec9e75c0700a57ddc6 |
| institution | DOAJ |
| issn | 2309-608X |
| language | English |
| publishDate | 2025-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Fungi |
| spelling | doaj-art-2d9f0b31285745ec9e75c0700a57ddc62025-08-20T02:42:32ZengMDPI AGJournal of Fungi2309-608X2025-03-0111321310.3390/jof11030213Fungal Stress Responses and the Importance of GPCRsDaniela Lara-Martínez0Fabiola Estefania Tristán-Flores1Juan Antonio Cervantes-Montelongo2Guillermo Antonio Silva-Martínez3Posgrado de Ingeniería Bioquímica, Departamento de Ingeniería Bioquímica y Ambiental, Tecnológico Nacional de México en Celaya, Celaya 38010, Guanajuato, MexicoPosgrado de Ingeniería Bioquímica, Departamento de Ingeniería Bioquímica y Ambiental, Tecnológico Nacional de México en Celaya, Celaya 38010, Guanajuato, MexicoDepartamento de Ingeniería Bioquímica y Ambiental, Tecnológico Nacional de México en Celaya, Celaya 38010, Guanajuato, MexicoPosgrado de Ingeniería Bioquímica, Departamento de Ingeniería Bioquímica y Ambiental, Tecnológico Nacional de México en Celaya, Celaya 38010, Guanajuato, MexicoG-protein-coupled receptors (GPCRs) play a crucial role in the gene regulation of processes related to the response to different types of stress in fungi. These receptors act as sensors of extracellular signals and transmit the information to the interior of the cell through G-proteins. In the presence of different and specific types of stresses, GPCRs activate signaling cascades that culminate in the activation of transcription factors, which regulate the expression of genes associated with the stress response, including those induced by changes in environmental pH. GPCR-mediated gene regulation allows fungi to adapt to adverse conditions such as osmotic, thermal, oxidative, or nutritional stress, as well as fluctuations in environmental pH. This review focuses on the understanding of how GPCRs modulate the stress response in fungi and their crucial role in advancing our knowledge of the physiology and adaptability of these microorganisms in their changing environment.https://www.mdpi.com/2309-608X/11/3/213G-protein-coupled receptors (GPCRs)fungal stress responsegene regulationenvironmental adaptationsignal transduction |
| spellingShingle | Daniela Lara-Martínez Fabiola Estefania Tristán-Flores Juan Antonio Cervantes-Montelongo Guillermo Antonio Silva-Martínez Fungal Stress Responses and the Importance of GPCRs Journal of Fungi G-protein-coupled receptors (GPCRs) fungal stress response gene regulation environmental adaptation signal transduction |
| title | Fungal Stress Responses and the Importance of GPCRs |
| title_full | Fungal Stress Responses and the Importance of GPCRs |
| title_fullStr | Fungal Stress Responses and the Importance of GPCRs |
| title_full_unstemmed | Fungal Stress Responses and the Importance of GPCRs |
| title_short | Fungal Stress Responses and the Importance of GPCRs |
| title_sort | fungal stress responses and the importance of gpcrs |
| topic | G-protein-coupled receptors (GPCRs) fungal stress response gene regulation environmental adaptation signal transduction |
| url | https://www.mdpi.com/2309-608X/11/3/213 |
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