MicroRNA-140-5p inhibits cellular proliferation, migration and invasion by downregulating AKT/STAT3/NF-κB pathway in breast carcinoma cells

MicroRNA-140-5p inhibits cellular proliferation, migration and invasion by downregulating AKT/STAT3/NF-κB pathway in breast carcinoma cells

MicroRNA-140-5p (miR-140-5p) plays a pivotal role in human cancers. However, its role and molecular mechanisms in breast carcinoma are not fully explored. Using miR-140-5p transfected breast cancer cell line MDA-MB-231, several in vitro experiments were performed and described in this paper. They co...

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Bibliographic Details
Main Authors: Hou Lingli, Liu Qi, Zhao Ying, Yang Hongwei, Meng Qingying, Yu Fei
Format: Article
Language:English
Published: Sciendo 2022-12-01
Series:Acta Pharmaceutica
Subjects:
breast cancer
microrna-140-5p
cell proliferation
tumor progression
akt/stat3/nf-κb
Online Access:https://doi.org/10.2478/acph-2022-0039
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https://doi.org/10.2478/acph-2022-0039

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