Broad-range polymerase chain reaction and sequencing for the diagnosis of infectious diseases

Broad-range polymerase chain reaction and sequencing for the diagnosis of infectious diseases

ABSTRACT Broad-range polymerase chain reaction (BR-PCR) identifies molecular signatures of microorganisms directly from clinical specimens without requiring microbial growth in culture. BR-PCR may be a powerful tool to reveal microbial causes of infectious diseases, but the impact on diagnosis and c...

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Bibliographic Details
Main Authors:	Nicole E. Putnam, Drew W. Charles, James B. Doub, J. Kristie Johnson
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-04-01
Series:	Microbiology Spectrum
Subjects:	molecular diagnostics broad range PCR universal PCR 16S rDNA infectious disease diagnostics
Online Access:	https://journals.asm.org/doi/10.1128/spectrum.02505-24
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