Funicular Myelosis in a Butcher: It Was the Cream Cans

Background. Funicular myelosis is a known consequence of exposure to nitrous oxide. Nevertheless, there are only a few clinical trials assessing its long-term effects and there is no literature about the role of nutritional vitamin B12 supplementation in the context of nitrous oxide abuse. Case Desc...

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Main Authors: Fabian Wolpert, Krisztina Baráth, Janis Brakowski, Roland Renzel, Michael Linnebank, Andreas R. Gantenbein
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2015/827168
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author Fabian Wolpert
Krisztina Baráth
Janis Brakowski
Roland Renzel
Michael Linnebank
Andreas R. Gantenbein
author_facet Fabian Wolpert
Krisztina Baráth
Janis Brakowski
Roland Renzel
Michael Linnebank
Andreas R. Gantenbein
author_sort Fabian Wolpert
collection DOAJ
description Background. Funicular myelosis is a known consequence of exposure to nitrous oxide. Nevertheless, there are only a few clinical trials assessing its long-term effects and there is no literature about the role of nutritional vitamin B12 supplementation in the context of nitrous oxide abuse. Case Descriptions. We diagnosed funicular myelosis in a young butcher, who consumed high amounts of meat regularly. Since the diagnostic process did not reveal any metabolic causes, reinterrogation of the patient uncovered recreational abuse of nitrous oxide out of whipped cream can gas cartridges. After stopping abuse and supplementation of vitamin B12, the patient recovered almost completely. Conclusions. In our case, even high nutritional vitamin B12 uptake could not compensate the noxious effects of nitrous oxide. Since there are emerging reports of increasing misuse, this should be considered in the diagnostic and therapeutic care of patients with nitrous oxide abuse. Furthermore, our case emphasizes that patients with vitamin B12 deficiency should be assessed for nitrous oxide abuse.
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institution Kabale University
issn 2090-6668
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spelling doaj-art-2d69a9fad2524fa78eb97281e42696ec2025-02-03T01:23:05ZengWileyCase Reports in Neurological Medicine2090-66682090-66762015-01-01201510.1155/2015/827168827168Funicular Myelosis in a Butcher: It Was the Cream CansFabian Wolpert0Krisztina Baráth1Janis Brakowski2Roland Renzel3Michael Linnebank4Andreas R. Gantenbein5Department of Neurology, University Hospital Zürich, Frauenklinikstrasse 26, 8091 Zürich, SwitzerlandMedizinisch Radiologisches Institut (MRI Bethanien), Toblerstrasse 51, Bahnhofplatz, Stadelhofen, 8044 Zürich, SwitzerlandDepartment of Psychiatry, Psychotherapy and Psychosomatics, Hospital of Psychiatry, University of Zurich, Lenggstrasse 31, 8032 Zürich, SwitzerlandDepartment of Neurology, University Hospital Zürich, Frauenklinikstrasse 26, 8091 Zürich, SwitzerlandDepartment of Neurology, University Hospital Zürich, Frauenklinikstrasse 26, 8091 Zürich, SwitzerlandDepartment of Neurology, University Hospital Zürich, Frauenklinikstrasse 26, 8091 Zürich, SwitzerlandBackground. Funicular myelosis is a known consequence of exposure to nitrous oxide. Nevertheless, there are only a few clinical trials assessing its long-term effects and there is no literature about the role of nutritional vitamin B12 supplementation in the context of nitrous oxide abuse. Case Descriptions. We diagnosed funicular myelosis in a young butcher, who consumed high amounts of meat regularly. Since the diagnostic process did not reveal any metabolic causes, reinterrogation of the patient uncovered recreational abuse of nitrous oxide out of whipped cream can gas cartridges. After stopping abuse and supplementation of vitamin B12, the patient recovered almost completely. Conclusions. In our case, even high nutritional vitamin B12 uptake could not compensate the noxious effects of nitrous oxide. Since there are emerging reports of increasing misuse, this should be considered in the diagnostic and therapeutic care of patients with nitrous oxide abuse. Furthermore, our case emphasizes that patients with vitamin B12 deficiency should be assessed for nitrous oxide abuse.http://dx.doi.org/10.1155/2015/827168
spellingShingle Fabian Wolpert
Krisztina Baráth
Janis Brakowski
Roland Renzel
Michael Linnebank
Andreas R. Gantenbein
Funicular Myelosis in a Butcher: It Was the Cream Cans
Case Reports in Neurological Medicine
title Funicular Myelosis in a Butcher: It Was the Cream Cans
title_full Funicular Myelosis in a Butcher: It Was the Cream Cans
title_fullStr Funicular Myelosis in a Butcher: It Was the Cream Cans
title_full_unstemmed Funicular Myelosis in a Butcher: It Was the Cream Cans
title_short Funicular Myelosis in a Butcher: It Was the Cream Cans
title_sort funicular myelosis in a butcher it was the cream cans
url http://dx.doi.org/10.1155/2015/827168
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