Extradigestive Manifestation of Helicobacter Pylori Infection in Children and Adolescents
Helicobacter pylori infection fulfills each of Koch's postulates as a human pathogen causing chronic active gastritis. Disease consequences that develop in a subset of infected subjects include peptic ulcerations, gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. More recen...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2005-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2005/971974 |
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| _version_ | 1832565149808984064 |
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| author | Philip M Sherman Frank YH Lin |
| author_facet | Philip M Sherman Frank YH Lin |
| author_sort | Philip M Sherman |
| collection | DOAJ |
| description | Helicobacter pylori infection fulfills each of Koch's postulates as a human pathogen causing chronic active gastritis. Disease consequences that develop in a subset of infected subjects include peptic ulcerations, gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. More recently, multiple publications have advocated a role for H pylori infection in causing a variety of extraintestinal manifestations. Many of these reports suffer from being case reports or case series without adequate controls. As a result, purported manifestations may simply be coincidental in nature. On the other hand, increasing evidence supports H pylori infection as a cause of sideropenic (refractory iron deficiency) anemia. Moderate evidence supports H pylori gastric infection as a cause of some cases of immune thrombocytopenic purpura due to molecular mimicry. Guidelines should be adjusted in accordance with advancing knowledge in the field. |
| format | Article |
| id | doaj-art-2d4b6c07a3934e30bd6817c0f6ad7055 |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 2005-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-2d4b6c07a3934e30bd6817c0f6ad70552025-02-03T01:09:09ZengWileyCanadian Journal of Gastroenterology0835-79002005-01-0119742142410.1155/2005/971974Extradigestive Manifestation of Helicobacter Pylori Infection in Children and AdolescentsPhilip M Sherman0Frank YH Lin1Research Institute, Hospital for Sick Children, University of Toronto, Toronto, Ontario, CanadaResearch Institute, Hospital for Sick Children, University of Toronto, Toronto, Ontario, CanadaHelicobacter pylori infection fulfills each of Koch's postulates as a human pathogen causing chronic active gastritis. Disease consequences that develop in a subset of infected subjects include peptic ulcerations, gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. More recently, multiple publications have advocated a role for H pylori infection in causing a variety of extraintestinal manifestations. Many of these reports suffer from being case reports or case series without adequate controls. As a result, purported manifestations may simply be coincidental in nature. On the other hand, increasing evidence supports H pylori infection as a cause of sideropenic (refractory iron deficiency) anemia. Moderate evidence supports H pylori gastric infection as a cause of some cases of immune thrombocytopenic purpura due to molecular mimicry. Guidelines should be adjusted in accordance with advancing knowledge in the field.http://dx.doi.org/10.1155/2005/971974 |
| spellingShingle | Philip M Sherman Frank YH Lin Extradigestive Manifestation of Helicobacter Pylori Infection in Children and Adolescents Canadian Journal of Gastroenterology |
| title | Extradigestive Manifestation of Helicobacter Pylori Infection in Children and Adolescents |
| title_full | Extradigestive Manifestation of Helicobacter Pylori Infection in Children and Adolescents |
| title_fullStr | Extradigestive Manifestation of Helicobacter Pylori Infection in Children and Adolescents |
| title_full_unstemmed | Extradigestive Manifestation of Helicobacter Pylori Infection in Children and Adolescents |
| title_short | Extradigestive Manifestation of Helicobacter Pylori Infection in Children and Adolescents |
| title_sort | extradigestive manifestation of helicobacter pylori infection in children and adolescents |
| url | http://dx.doi.org/10.1155/2005/971974 |
| work_keys_str_mv | AT philipmsherman extradigestivemanifestationofhelicobacterpyloriinfectioninchildrenandadolescents AT frankyhlin extradigestivemanifestationofhelicobacterpyloriinfectioninchildrenandadolescents |