Exploring the dual role of Mangifera indica L. in regulating immune response and pain persistence in inflammatory bowel disease

Exploring the dual role of Mangifera indica L. in regulating immune response and pain persistence in inflammatory bowel disease

Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn’s disease, is characterized by chronic intestinal inflammation and immune dysregulation, driven mainly by Th1 and Th17 cells and sustained by pro-inflammatory cyto-chemokines. This inflammatory milieu is associated with visc...

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Main Authors: Elena Lucarini, Anna Schettino, Noemi Marigliano, Clara Ciampi, Martina Smimmo, Francesca Romano, Antonio Paolillo, Luana Izzo, Jenefa Begum, Adel Abo Mansour, Nunzia Iaccarino, Antonio Randazzo, Karin Vicente Greco, Raffaele Scarpa, Francesco Caso, Asif Jilani Iqbal, Mariarosaria Bucci, Carla Ghelardini, Lorenzo Di Cesare Mannelli, Anella Saviano, Francesco Maione
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Pharmacological Research
Subjects:
Functional foods
Inflammatory bowel disease
Mangiferin
Mangifera indica L.
Nutraceuticals
Visceral hypersensitivity
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661825001987
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http://www.sciencedirect.com/science/article/pii/S1043661825001987

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