Effect of frailty on the short-term functional outcome of elderly patients with traumatic brain injury
[Objective] To investigate the effect of frailty on the short-term functional outcome of elderly patients with traumatic brain injury. [Methods] A retrospective analysis was conducted on 127 elderly patients with traumatic brain injury admitted to Hai’an People’s Hospital from April 2019 to April 20...
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| Format: | Article |
| Language: | zho |
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Editorial Office of International Journal of Geriatrics
2025-01-01
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| Series: | Guoji laonian yixue zazhi |
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| Online Access: | http://gwll.publish.founderss.cn/thesisDetails#10.3969/j.issn.1674-7593.2025.01.014&lang=en |
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| _version_ | 1832592776923971584 |
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| author | Yujing Gu Huiqin Cui Yang Gu Xiaojiang Liu |
| author_facet | Yujing Gu Huiqin Cui Yang Gu Xiaojiang Liu |
| author_sort | Yujing Gu |
| collection | DOAJ |
| description | [Objective] To investigate the effect of frailty on the short-term functional outcome of elderly patients with traumatic brain injury. [Methods] A retrospective analysis was conducted on 127 elderly patients with traumatic brain injury admitted to Hai’an People’s Hospital from April 2019 to April 2022.General information, demographics, clinical indicators and imaging results were collected.The clinical frailty scale that provides an assessment of the presence and severity of frailty was applied.The in-hospital mortality and neurological status at 3 months of onset were compared between the frail and non-frail groups.Multivariate logistic regression were used to clarify the factors affecting the prognosis of patients' neurological function, and clarify the predictive power of Glasgow coma scale and logistic regression model for neurological function prognosis through ROC curve analysis. [Results] Among the 127 elderly patients with traumatic brain injury, 48 cases had frailty.A total of 34 patients died during hospitalization, and 63 patients had poor neurological outcome at 3 months follow-up.Compared with the non-frailty group, the frailty group was older, had a higher mortality rate during hospitalization, and had a higher proportion of poor neurological prognosis at 3 months after onset (P<0.05).Multivariate logistics regression analysis shows that age >75 years old, higher Glasgow coma score and clinical frailty score ≥5 were independent risk factors for poor neurological prognosis in elderly patients with traumatic brain injury at 3 months onset.The results of the ROC curve indicated that the area under the curve of the Glasgow coma score predicting poor neurological prognosis in elderly patients with traumatic brain injury at 3 months after onset was 0.643 (95%CI:0.532-0.727), which was increased to 0.874 (95%CI:0.782-0.931) when indicators of patient age, Glasgow coma score and clinical frailty score were applied. [Conclusion] Elderly traumatic brain injury patients with frailty have higher mortality and unfavorable prognosis that deserves clinical attention. |
| format | Article |
| id | doaj-art-2d3ee5193edd4a37912efd6c9bc6e663 |
| institution | Kabale University |
| issn | 1674-7593 |
| language | zho |
| publishDate | 2025-01-01 |
| publisher | Editorial Office of International Journal of Geriatrics |
| record_format | Article |
| series | Guoji laonian yixue zazhi |
| spelling | doaj-art-2d3ee5193edd4a37912efd6c9bc6e6632025-01-21T02:59:39ZzhoEditorial Office of International Journal of GeriatricsGuoji laonian yixue zazhi1674-75932025-01-01461687210.3969/j.issn.1674-7593.2025.01.014Effect of frailty on the short-term functional outcome of elderly patients with traumatic brain injuryYujing Gu0Huiqin Cui1Yang Gu2Xiaojiang Liu3Department of Trauma Surgery, Hai’an People’s Hospital, Hai’an 226600Department of Trauma Surgery, Hai’an People’s Hospital, Hai’an 226600Department of Trauma Surgery, Hai’an People’s Hospital, Hai’an 226600Department of Neurosurgery, Hai’an People’s Hospital, Hai’an 226600[Objective] To investigate the effect of frailty on the short-term functional outcome of elderly patients with traumatic brain injury. [Methods] A retrospective analysis was conducted on 127 elderly patients with traumatic brain injury admitted to Hai’an People’s Hospital from April 2019 to April 2022.General information, demographics, clinical indicators and imaging results were collected.The clinical frailty scale that provides an assessment of the presence and severity of frailty was applied.The in-hospital mortality and neurological status at 3 months of onset were compared between the frail and non-frail groups.Multivariate logistic regression were used to clarify the factors affecting the prognosis of patients' neurological function, and clarify the predictive power of Glasgow coma scale and logistic regression model for neurological function prognosis through ROC curve analysis. [Results] Among the 127 elderly patients with traumatic brain injury, 48 cases had frailty.A total of 34 patients died during hospitalization, and 63 patients had poor neurological outcome at 3 months follow-up.Compared with the non-frailty group, the frailty group was older, had a higher mortality rate during hospitalization, and had a higher proportion of poor neurological prognosis at 3 months after onset (P<0.05).Multivariate logistics regression analysis shows that age >75 years old, higher Glasgow coma score and clinical frailty score ≥5 were independent risk factors for poor neurological prognosis in elderly patients with traumatic brain injury at 3 months onset.The results of the ROC curve indicated that the area under the curve of the Glasgow coma score predicting poor neurological prognosis in elderly patients with traumatic brain injury at 3 months after onset was 0.643 (95%CI:0.532-0.727), which was increased to 0.874 (95%CI:0.782-0.931) when indicators of patient age, Glasgow coma score and clinical frailty score were applied. [Conclusion] Elderly traumatic brain injury patients with frailty have higher mortality and unfavorable prognosis that deserves clinical attention.http://gwll.publish.founderss.cn/thesisDetails#10.3969/j.issn.1674-7593.2025.01.014&lang=enfrailtytraumatic brain injuryshort-term functional outcome |
| spellingShingle | Yujing Gu Huiqin Cui Yang Gu Xiaojiang Liu Effect of frailty on the short-term functional outcome of elderly patients with traumatic brain injury Guoji laonian yixue zazhi frailty traumatic brain injury short-term functional outcome |
| title | Effect of frailty on the short-term functional outcome of elderly patients with traumatic brain injury |
| title_full | Effect of frailty on the short-term functional outcome of elderly patients with traumatic brain injury |
| title_fullStr | Effect of frailty on the short-term functional outcome of elderly patients with traumatic brain injury |
| title_full_unstemmed | Effect of frailty on the short-term functional outcome of elderly patients with traumatic brain injury |
| title_short | Effect of frailty on the short-term functional outcome of elderly patients with traumatic brain injury |
| title_sort | effect of frailty on the short term functional outcome of elderly patients with traumatic brain injury |
| topic | frailty traumatic brain injury short-term functional outcome |
| url | http://gwll.publish.founderss.cn/thesisDetails#10.3969/j.issn.1674-7593.2025.01.014&lang=en |
| work_keys_str_mv | AT yujinggu effectoffrailtyontheshorttermfunctionaloutcomeofelderlypatientswithtraumaticbraininjury AT huiqincui effectoffrailtyontheshorttermfunctionaloutcomeofelderlypatientswithtraumaticbraininjury AT yanggu effectoffrailtyontheshorttermfunctionaloutcomeofelderlypatientswithtraumaticbraininjury AT xiaojiangliu effectoffrailtyontheshorttermfunctionaloutcomeofelderlypatientswithtraumaticbraininjury |