A Review of Collagen Cross-Linking in Cornea and Sclera
Riboflavin/UVA cross-linking is a technique introduced in the past decades for the treatment of keratoconus, keratectasia, and infectious keratitis. Its efficacy and safety have been investigated with clinical and laboratory studies since its first clinical application by Wollensak for the treatment...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2015/289467 |
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| author | Xiao Zhang Xiang-chen Tao Jian Zhang Zhi-wei Li Yan-yun Xu Yu-meng Wang Chun-xiao Zhang Guo-ying Mu |
| author_facet | Xiao Zhang Xiang-chen Tao Jian Zhang Zhi-wei Li Yan-yun Xu Yu-meng Wang Chun-xiao Zhang Guo-ying Mu |
| author_sort | Xiao Zhang |
| collection | DOAJ |
| description | Riboflavin/UVA cross-linking is a technique introduced in the past decades for the treatment of keratoconus, keratectasia, and infectious keratitis. Its efficacy and safety have been investigated with clinical and laboratory studies since its first clinical application by Wollensak for the treatment of keratoconus. Although its complications are encountered during clinical practice, such as infection inducing risk, minimal invasion merits a further investigation on its future application in clinical practice. Recently, collagen cross-linking in sclera shows a promising prospect. In present study, we summarized the representative studies describing the clinical and laboratory application of collagen cross-linking published in past decades and provided our opinion on the positive and negative results of cross-linking in the treatment of ophthalmic disorders. |
| format | Article |
| id | doaj-art-2d2d43f954bd41abbb434d116e547f8f |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-2d2d43f954bd41abbb434d116e547f8f2025-02-03T06:12:23ZengWileyJournal of Ophthalmology2090-004X2090-00582015-01-01201510.1155/2015/289467289467A Review of Collagen Cross-Linking in Cornea and ScleraXiao Zhang0Xiang-chen Tao1Jian Zhang2Zhi-wei Li3Yan-yun Xu4Yu-meng Wang5Chun-xiao Zhang6Guo-ying Mu7Department of Ophthalmology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong 250000, ChinaDepartment of Ophthalmology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong 250000, ChinaZibo Eye Hospital, No. 33-6, Songlingxi Street, Zichuan, Zibo, Shandong 255100, ChinaDepartment of Ophthalmology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong 250000, ChinaDepartment of Ophthalmology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong 250000, ChinaDepartment of Ophthalmology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong 250000, ChinaDepartment of Ophthalmology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong 250000, ChinaDepartment of Ophthalmology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong 250000, ChinaRiboflavin/UVA cross-linking is a technique introduced in the past decades for the treatment of keratoconus, keratectasia, and infectious keratitis. Its efficacy and safety have been investigated with clinical and laboratory studies since its first clinical application by Wollensak for the treatment of keratoconus. Although its complications are encountered during clinical practice, such as infection inducing risk, minimal invasion merits a further investigation on its future application in clinical practice. Recently, collagen cross-linking in sclera shows a promising prospect. In present study, we summarized the representative studies describing the clinical and laboratory application of collagen cross-linking published in past decades and provided our opinion on the positive and negative results of cross-linking in the treatment of ophthalmic disorders.http://dx.doi.org/10.1155/2015/289467 |
| spellingShingle | Xiao Zhang Xiang-chen Tao Jian Zhang Zhi-wei Li Yan-yun Xu Yu-meng Wang Chun-xiao Zhang Guo-ying Mu A Review of Collagen Cross-Linking in Cornea and Sclera Journal of Ophthalmology |
| title | A Review of Collagen Cross-Linking in Cornea and Sclera |
| title_full | A Review of Collagen Cross-Linking in Cornea and Sclera |
| title_fullStr | A Review of Collagen Cross-Linking in Cornea and Sclera |
| title_full_unstemmed | A Review of Collagen Cross-Linking in Cornea and Sclera |
| title_short | A Review of Collagen Cross-Linking in Cornea and Sclera |
| title_sort | review of collagen cross linking in cornea and sclera |
| url | http://dx.doi.org/10.1155/2015/289467 |
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