Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - II

Simple, accurate and reproducible visible spectrophotometric method for the assay of drugs such as pyrilamine and fluvoxamine as maleates was established based on the formation of charge-transfer complex and redox reaction between the corresponding drug and substituted p-benzoquinone (chloranilic...

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Main Authors: V. Annapurna, G. Jyothi, T. Rohini Kumari, B. B. V. Sailaja
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2010/306858
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author V. Annapurna
G. Jyothi
T. Rohini Kumari
B. B. V. Sailaja
author_facet V. Annapurna
G. Jyothi
T. Rohini Kumari
B. B. V. Sailaja
author_sort V. Annapurna
collection DOAJ
description Simple, accurate and reproducible visible spectrophotometric method for the assay of drugs such as pyrilamine and fluvoxamine as maleates was established based on the formation of charge-transfer complex and redox reaction between the corresponding drug and substituted p-benzoquinone (chloranilic acid). The optical characteristics such as Beer’s law limits, molar absorptivity and Sandell’s sensitivity are reported. Regression analysis using the method of least squares was made to evaluate the slope (b), intercept (a) and correlation coefficient (r) and standard error of estimation (Se) for each drug.
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institution Kabale University
issn 0973-4945
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language English
publishDate 2010-01-01
publisher Wiley
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series E-Journal of Chemistry
spelling doaj-art-2d1bd2695d2248d08ecf7be41dd8d11f2025-02-03T01:07:53ZengWileyE-Journal of Chemistry0973-49452090-98102010-01-017262462810.1155/2010/306858Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - IIV. Annapurna0G. Jyothi1T. Rohini Kumari2B. B. V. Sailaja3Department of chemistry, St. Theresa’s College for Women, Eluru-534003, IndiaDepartment of chemistry, St. Theresa’s College for Women, Eluru-534003, IndiaDepartment of chemistry, St. Theresa’s College for Women, Eluru-534003, IndiaAndhra University, Visakhapatnam, Andhra Pradesh, IndiaSimple, accurate and reproducible visible spectrophotometric method for the assay of drugs such as pyrilamine and fluvoxamine as maleates was established based on the formation of charge-transfer complex and redox reaction between the corresponding drug and substituted p-benzoquinone (chloranilic acid). The optical characteristics such as Beer’s law limits, molar absorptivity and Sandell’s sensitivity are reported. Regression analysis using the method of least squares was made to evaluate the slope (b), intercept (a) and correlation coefficient (r) and standard error of estimation (Se) for each drug.http://dx.doi.org/10.1155/2010/306858
spellingShingle V. Annapurna
G. Jyothi
T. Rohini Kumari
B. B. V. Sailaja
Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - II
E-Journal of Chemistry
title Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - II
title_full Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - II
title_fullStr Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - II
title_full_unstemmed Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - II
title_short Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - II
title_sort spectrophotometric determination of various drugs using chloranilic acid as chromogenic reagent ii
url http://dx.doi.org/10.1155/2010/306858
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AT trohinikumari spectrophotometricdeterminationofvariousdrugsusingchloranilicacidaschromogenicreagentii
AT bbvsailaja spectrophotometricdeterminationofvariousdrugsusingchloranilicacidaschromogenicreagentii