Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - II
Simple, accurate and reproducible visible spectrophotometric method for the assay of drugs such as pyrilamine and fluvoxamine as maleates was established based on the formation of charge-transfer complex and redox reaction between the corresponding drug and substituted p-benzoquinone (chloranilic...
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Format: | Article |
Language: | English |
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Wiley
2010-01-01
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Series: | E-Journal of Chemistry |
Online Access: | http://dx.doi.org/10.1155/2010/306858 |
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author | V. Annapurna G. Jyothi T. Rohini Kumari B. B. V. Sailaja |
author_facet | V. Annapurna G. Jyothi T. Rohini Kumari B. B. V. Sailaja |
author_sort | V. Annapurna |
collection | DOAJ |
description | Simple, accurate and reproducible visible spectrophotometric method for the assay of drugs such as pyrilamine and fluvoxamine as maleates was established based on the formation of charge-transfer complex and redox reaction between the corresponding drug and substituted p-benzoquinone (chloranilic acid). The optical characteristics such as Beer’s law limits, molar absorptivity and Sandell’s sensitivity are reported. Regression analysis using the method of least squares was made to evaluate the slope (b), intercept (a) and correlation coefficient (r) and standard error of estimation (Se) for each drug. |
format | Article |
id | doaj-art-2d1bd2695d2248d08ecf7be41dd8d11f |
institution | Kabale University |
issn | 0973-4945 2090-9810 |
language | English |
publishDate | 2010-01-01 |
publisher | Wiley |
record_format | Article |
series | E-Journal of Chemistry |
spelling | doaj-art-2d1bd2695d2248d08ecf7be41dd8d11f2025-02-03T01:07:53ZengWileyE-Journal of Chemistry0973-49452090-98102010-01-017262462810.1155/2010/306858Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - IIV. Annapurna0G. Jyothi1T. Rohini Kumari2B. B. V. Sailaja3Department of chemistry, St. Theresa’s College for Women, Eluru-534003, IndiaDepartment of chemistry, St. Theresa’s College for Women, Eluru-534003, IndiaDepartment of chemistry, St. Theresa’s College for Women, Eluru-534003, IndiaAndhra University, Visakhapatnam, Andhra Pradesh, IndiaSimple, accurate and reproducible visible spectrophotometric method for the assay of drugs such as pyrilamine and fluvoxamine as maleates was established based on the formation of charge-transfer complex and redox reaction between the corresponding drug and substituted p-benzoquinone (chloranilic acid). The optical characteristics such as Beer’s law limits, molar absorptivity and Sandell’s sensitivity are reported. Regression analysis using the method of least squares was made to evaluate the slope (b), intercept (a) and correlation coefficient (r) and standard error of estimation (Se) for each drug.http://dx.doi.org/10.1155/2010/306858 |
spellingShingle | V. Annapurna G. Jyothi T. Rohini Kumari B. B. V. Sailaja Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - II E-Journal of Chemistry |
title | Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - II |
title_full | Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - II |
title_fullStr | Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - II |
title_full_unstemmed | Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - II |
title_short | Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - II |
title_sort | spectrophotometric determination of various drugs using chloranilic acid as chromogenic reagent ii |
url | http://dx.doi.org/10.1155/2010/306858 |
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