Temporal Analysis of the Incidence, Mortality and Disability-Adjusted Life Years of Benign Gallbladder and Biliary Diseases in High-Income Nations, 1990–2019
Objective:. The aim of this observational study was to analyze trends in the incidence, mortality, and disability-adjusted life years (DALYs) of benign gallbladder and biliary diseases across high-income countries between 1990 and 2019. Background:. Benign gallbladder and biliary diseases place a su...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Health
2024-06-01
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| Series: | Annals of Surgery Open |
| Online Access: | http://journals.lww.com/10.1097/AS9.0000000000000453 |
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| author | Dominic W. Proctor, BMBS, MSc Richard Goodall, BSc, MBChB, MRCS, FHEA Kim Borsky, MBBS, MMRCS Justin D. Salciccioli, MBBS, MA Dominic C. Marshall, MBBS, MRCP, BSc Kumaran Shanmugarajah, MD, PhD Joseph Shalhoub, BSc, MBBS, FHEA, PhD, DIC, MEd, FFSTEd, FRCS, FEBVS |
| author_facet | Dominic W. Proctor, BMBS, MSc Richard Goodall, BSc, MBChB, MRCS, FHEA Kim Borsky, MBBS, MMRCS Justin D. Salciccioli, MBBS, MA Dominic C. Marshall, MBBS, MRCP, BSc Kumaran Shanmugarajah, MD, PhD Joseph Shalhoub, BSc, MBBS, FHEA, PhD, DIC, MEd, FFSTEd, FRCS, FEBVS |
| author_sort | Dominic W. Proctor, BMBS, MSc |
| collection | DOAJ |
| description | Objective:. The aim of this observational study was to analyze trends in the incidence, mortality, and disability-adjusted life years (DALYs) of benign gallbladder and biliary diseases across high-income countries between 1990 and 2019.
Background:. Benign gallbladder and biliary diseases place a substantial burden on healthcare systems in high-income countries. Accurate characterization of the disease burden may help optimize healthcare policy and resource distribution.
Materials and methods:. Age-standardized incidence rates (ASIRs), age-standardized mortality rates (ASMRs), and DALYs data for gallbladder and biliary diseases in males and females were extracted from the 2019 Global Burden of Disease (GBD) study. A mortality-incidence index (MII) was also calculated. Joinpoint regression analysis was performed.
Results:. The median ASIRs across the European Union 15+ countries in 2019 were 758/100,000 for females and 282/100,000 for males. Between 1990 and 2019 the median percentage change in ASIR was +2.49% for females and +1.07% for males. The median ASMRs in 2019 were 1.22/100,000 for females and 1.49/100,000 for males with a median percentage change over the observation period of −21.93% and −23.01%, respectively. In 2019, the median DALYs was 65/100,000 for females and 37/100,000 among males, with comparable percentage decreases over the observation period of −21.27% and −19.23%, respectively.
Conclusions:. International variation in lifestyle factors, diagnostic and management strategies likely account for national and sex disparities. This study highlights the importance of ongoing clinical efforts to optimize treatment pathways for gallbladder and biliary diseases, particularly in the provision of emergency surgical services and efforts to address population risk factors. |
| format | Article |
| id | doaj-art-2d0cd5ee22144364a974b6f754bc4cf5 |
| institution | Kabale University |
| issn | 2691-3593 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Wolters Kluwer Health |
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| series | Annals of Surgery Open |
| spelling | doaj-art-2d0cd5ee22144364a974b6f754bc4cf52025-01-24T09:18:39ZengWolters Kluwer HealthAnnals of Surgery Open2691-35932024-06-0152e45310.1097/AS9.0000000000000453202406000-00048Temporal Analysis of the Incidence, Mortality and Disability-Adjusted Life Years of Benign Gallbladder and Biliary Diseases in High-Income Nations, 1990–2019Dominic W. Proctor, BMBS, MSc0Richard Goodall, BSc, MBChB, MRCS, FHEA1Kim Borsky, MBBS, MMRCS2Justin D. Salciccioli, MBBS, MA3Dominic C. Marshall, MBBS, MRCP, BSc4Kumaran Shanmugarajah, MD, PhD5Joseph Shalhoub, BSc, MBBS, FHEA, PhD, DIC, MEd, FFSTEd, FRCS, FEBVS6From the * Department of Undergraduate Medical Education, Royal Free London NHS Foundation Trust, London, UK† Department of Surgery and Cancer, Imperial College London, UK‡ Department of Plastic Surgery, Salisbury Hospital, Salisbury, UK§ Department of Medicine, Mount Auburn Hospital, Harvard Medical School, Cambridge, MA† Department of Surgery and Cancer, Imperial College London, UK∥ Department of Surgery, University of Chicago Medicine, Chicago, IL† Department of Surgery and Cancer, Imperial College London, UKObjective:. The aim of this observational study was to analyze trends in the incidence, mortality, and disability-adjusted life years (DALYs) of benign gallbladder and biliary diseases across high-income countries between 1990 and 2019. Background:. Benign gallbladder and biliary diseases place a substantial burden on healthcare systems in high-income countries. Accurate characterization of the disease burden may help optimize healthcare policy and resource distribution. Materials and methods:. Age-standardized incidence rates (ASIRs), age-standardized mortality rates (ASMRs), and DALYs data for gallbladder and biliary diseases in males and females were extracted from the 2019 Global Burden of Disease (GBD) study. A mortality-incidence index (MII) was also calculated. Joinpoint regression analysis was performed. Results:. The median ASIRs across the European Union 15+ countries in 2019 were 758/100,000 for females and 282/100,000 for males. Between 1990 and 2019 the median percentage change in ASIR was +2.49% for females and +1.07% for males. The median ASMRs in 2019 were 1.22/100,000 for females and 1.49/100,000 for males with a median percentage change over the observation period of −21.93% and −23.01%, respectively. In 2019, the median DALYs was 65/100,000 for females and 37/100,000 among males, with comparable percentage decreases over the observation period of −21.27% and −19.23%, respectively. Conclusions:. International variation in lifestyle factors, diagnostic and management strategies likely account for national and sex disparities. This study highlights the importance of ongoing clinical efforts to optimize treatment pathways for gallbladder and biliary diseases, particularly in the provision of emergency surgical services and efforts to address population risk factors.http://journals.lww.com/10.1097/AS9.0000000000000453 |
| spellingShingle | Dominic W. Proctor, BMBS, MSc Richard Goodall, BSc, MBChB, MRCS, FHEA Kim Borsky, MBBS, MMRCS Justin D. Salciccioli, MBBS, MA Dominic C. Marshall, MBBS, MRCP, BSc Kumaran Shanmugarajah, MD, PhD Joseph Shalhoub, BSc, MBBS, FHEA, PhD, DIC, MEd, FFSTEd, FRCS, FEBVS Temporal Analysis of the Incidence, Mortality and Disability-Adjusted Life Years of Benign Gallbladder and Biliary Diseases in High-Income Nations, 1990–2019 Annals of Surgery Open |
| title | Temporal Analysis of the Incidence, Mortality and Disability-Adjusted Life Years of Benign Gallbladder and Biliary Diseases in High-Income Nations, 1990–2019 |
| title_full | Temporal Analysis of the Incidence, Mortality and Disability-Adjusted Life Years of Benign Gallbladder and Biliary Diseases in High-Income Nations, 1990–2019 |
| title_fullStr | Temporal Analysis of the Incidence, Mortality and Disability-Adjusted Life Years of Benign Gallbladder and Biliary Diseases in High-Income Nations, 1990–2019 |
| title_full_unstemmed | Temporal Analysis of the Incidence, Mortality and Disability-Adjusted Life Years of Benign Gallbladder and Biliary Diseases in High-Income Nations, 1990–2019 |
| title_short | Temporal Analysis of the Incidence, Mortality and Disability-Adjusted Life Years of Benign Gallbladder and Biliary Diseases in High-Income Nations, 1990–2019 |
| title_sort | temporal analysis of the incidence mortality and disability adjusted life years of benign gallbladder and biliary diseases in high income nations 1990 2019 |
| url | http://journals.lww.com/10.1097/AS9.0000000000000453 |
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