Point-of-Care Diagnoses and Assays Based on Lateral Flow Test

Analytical devices for point-of-care diagnoses are highly desired and would improve quality of life when first diagnoses are made early and pathologies are recognized soon. Lateral flow tests (LFTs) are such tools that can be easily performed without specific equipment, skills, or experiences. This...

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Main Author: Miroslav Pohanka
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:International Journal of Analytical Chemistry
Online Access:http://dx.doi.org/10.1155/2021/6685619
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author Miroslav Pohanka
author_facet Miroslav Pohanka
author_sort Miroslav Pohanka
collection DOAJ
description Analytical devices for point-of-care diagnoses are highly desired and would improve quality of life when first diagnoses are made early and pathologies are recognized soon. Lateral flow tests (LFTs) are such tools that can be easily performed without specific equipment, skills, or experiences. This review is focused on the use of LFT in point-of-care diagnoses. The principle of the assay is explained, and new materials like nanoparticles for labeling, new recognition molecules for interaction with an analyte, and new additional instrumentation like signal scaling by a smartphone camera are described and discussed. Advantages of the LFT devices as well as their limitations are described and discussed here considering actual papers that are properly cited.
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institution Kabale University
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spelling doaj-art-2d08cd4ae9814d9398933c58600bcded2025-02-03T01:20:44ZengWileyInternational Journal of Analytical Chemistry1687-87601687-87792021-01-01202110.1155/2021/66856196685619Point-of-Care Diagnoses and Assays Based on Lateral Flow TestMiroslav Pohanka0Faculty of Military Health Sciences, University of Defense, Trebesska 1575, Hradec Kralove CZ-50001, Czech RepublicAnalytical devices for point-of-care diagnoses are highly desired and would improve quality of life when first diagnoses are made early and pathologies are recognized soon. Lateral flow tests (LFTs) are such tools that can be easily performed without specific equipment, skills, or experiences. This review is focused on the use of LFT in point-of-care diagnoses. The principle of the assay is explained, and new materials like nanoparticles for labeling, new recognition molecules for interaction with an analyte, and new additional instrumentation like signal scaling by a smartphone camera are described and discussed. Advantages of the LFT devices as well as their limitations are described and discussed here considering actual papers that are properly cited.http://dx.doi.org/10.1155/2021/6685619
spellingShingle Miroslav Pohanka
Point-of-Care Diagnoses and Assays Based on Lateral Flow Test
International Journal of Analytical Chemistry
title Point-of-Care Diagnoses and Assays Based on Lateral Flow Test
title_full Point-of-Care Diagnoses and Assays Based on Lateral Flow Test
title_fullStr Point-of-Care Diagnoses and Assays Based on Lateral Flow Test
title_full_unstemmed Point-of-Care Diagnoses and Assays Based on Lateral Flow Test
title_short Point-of-Care Diagnoses and Assays Based on Lateral Flow Test
title_sort point of care diagnoses and assays based on lateral flow test
url http://dx.doi.org/10.1155/2021/6685619
work_keys_str_mv AT miroslavpohanka pointofcarediagnosesandassaysbasedonlateralflowtest