Comparisons between Arabidopsis thaliana and Drosophila melanogaster in relation to Coding and Noncoding Sequence Length and Gene Expression
There is a continuing interest in the analysis of gene architecture and gene expression to determine the relationship that may exist. Advances in high-quality sequencing technologies and large-scale resource datasets have increased the understanding of relationships and cross-referencing of expressi...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | International Journal of Genomics |
| Online Access: | http://dx.doi.org/10.1155/2015/269127 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832552112606674944 |
|---|---|
| author | Rachel Caldwell Yan-Xia Lin Ren Zhang |
| author_facet | Rachel Caldwell Yan-Xia Lin Ren Zhang |
| author_sort | Rachel Caldwell |
| collection | DOAJ |
| description | There is a continuing interest in the analysis of gene architecture and gene expression to determine the relationship that may exist. Advances in high-quality sequencing technologies and large-scale resource datasets have increased the understanding of relationships and cross-referencing of expression data to the large genome data. Although a negative correlation between expression level and gene (especially transcript) length has been generally accepted, there have been some conflicting results arising from the literature concerning the impacts of different regions of genes, and the underlying reason is not well understood. The research aims to apply quantile regression techniques for statistical analysis of coding and noncoding sequence length and gene expression data in the plant, Arabidopsis thaliana, and fruit fly, Drosophila melanogaster, to determine if a relationship exists and if there is any variation or similarities between these species. The quantile regression analysis found that the coding sequence length and gene expression correlations varied, and similarities emerged for the noncoding sequence length (5′ and 3′ UTRs) between animal and plant species. In conclusion, the information described in this study provides the basis for further exploration into gene regulation with regard to coding and noncoding sequence length. |
| format | Article |
| id | doaj-art-2cfefbc2cd2440b496c2dda71c36e4cb |
| institution | Kabale University |
| issn | 2314-436X 2314-4378 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Genomics |
| spelling | doaj-art-2cfefbc2cd2440b496c2dda71c36e4cb2025-02-03T05:59:33ZengWileyInternational Journal of Genomics2314-436X2314-43782015-01-01201510.1155/2015/269127269127Comparisons between Arabidopsis thaliana and Drosophila melanogaster in relation to Coding and Noncoding Sequence Length and Gene ExpressionRachel Caldwell0Yan-Xia Lin1Ren Zhang2School of Biological Sciences, University of Wollongong, Northfields Avenue, Keiraville, Wollongong, NSW 2522, AustraliaNational Institute for Applied Statistics Research Australia (NIASRA), School of Mathematics and Applied Statistics, University of Wollongong, Northfields Avenue, Keiraville, Wollongong, NSW 2522, AustraliaSchool of Biological Sciences, University of Wollongong, Northfields Avenue, Keiraville, Wollongong, NSW 2522, AustraliaThere is a continuing interest in the analysis of gene architecture and gene expression to determine the relationship that may exist. Advances in high-quality sequencing technologies and large-scale resource datasets have increased the understanding of relationships and cross-referencing of expression data to the large genome data. Although a negative correlation between expression level and gene (especially transcript) length has been generally accepted, there have been some conflicting results arising from the literature concerning the impacts of different regions of genes, and the underlying reason is not well understood. The research aims to apply quantile regression techniques for statistical analysis of coding and noncoding sequence length and gene expression data in the plant, Arabidopsis thaliana, and fruit fly, Drosophila melanogaster, to determine if a relationship exists and if there is any variation or similarities between these species. The quantile regression analysis found that the coding sequence length and gene expression correlations varied, and similarities emerged for the noncoding sequence length (5′ and 3′ UTRs) between animal and plant species. In conclusion, the information described in this study provides the basis for further exploration into gene regulation with regard to coding and noncoding sequence length.http://dx.doi.org/10.1155/2015/269127 |
| spellingShingle | Rachel Caldwell Yan-Xia Lin Ren Zhang Comparisons between Arabidopsis thaliana and Drosophila melanogaster in relation to Coding and Noncoding Sequence Length and Gene Expression International Journal of Genomics |
| title | Comparisons between Arabidopsis thaliana and Drosophila melanogaster in relation to Coding and Noncoding Sequence Length and Gene Expression |
| title_full | Comparisons between Arabidopsis thaliana and Drosophila melanogaster in relation to Coding and Noncoding Sequence Length and Gene Expression |
| title_fullStr | Comparisons between Arabidopsis thaliana and Drosophila melanogaster in relation to Coding and Noncoding Sequence Length and Gene Expression |
| title_full_unstemmed | Comparisons between Arabidopsis thaliana and Drosophila melanogaster in relation to Coding and Noncoding Sequence Length and Gene Expression |
| title_short | Comparisons between Arabidopsis thaliana and Drosophila melanogaster in relation to Coding and Noncoding Sequence Length and Gene Expression |
| title_sort | comparisons between arabidopsis thaliana and drosophila melanogaster in relation to coding and noncoding sequence length and gene expression |
| url | http://dx.doi.org/10.1155/2015/269127 |
| work_keys_str_mv | AT rachelcaldwell comparisonsbetweenarabidopsisthalianaanddrosophilamelanogasterinrelationtocodingandnoncodingsequencelengthandgeneexpression AT yanxialin comparisonsbetweenarabidopsisthalianaanddrosophilamelanogasterinrelationtocodingandnoncodingsequencelengthandgeneexpression AT renzhang comparisonsbetweenarabidopsisthalianaanddrosophilamelanogasterinrelationtocodingandnoncodingsequencelengthandgeneexpression |