FMRP cooperates with miRISC components to repress translation and regulate neurite morphogenesis in Drosophila

FMRP cooperates with miRISC components to repress translation and regulate neurite morphogenesis in Drosophila

Fragile X Syndrome (FXS) is the most common inherited form of intellectual disability and is caused by mutations in the gene encoding the Fragile X messenger ribonucleoprotein (FMRP). FMRP is an evolutionarily conserved and neuronally enriched RNA-binding protein (RBP) with functions in RNA editing,...

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Bibliographic Details
Main Authors: Navneeta Kaul, Sarala J. Pradhan, Nathan G. Boin, Madeleine M. Mason, Julian Rosales, Emily L. Starke, Emily C. Wilkinson, Erich G. Chapman, Scott A. Barbee
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:RNA Biology
Subjects:
Drosophila
FXS
FMRP
RNA-binding proteins
miRNA pathway
Online Access:https://www.tandfonline.com/doi/10.1080/15476286.2024.2392304
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