Light to Moderate Alcohol Consumption Is Protective for Type 2 Diabetes Mellitus in Normal Weight and Overweight Individuals but Not the Obese
Objective. To examine the association between alcohol consumption and risk of type 2 diabetes mellitus (T2DM) overall and by body mass index. Methods. Cross-sectional study of employed individuals. Daily alcohol intakes were calculated from a self-administered food frequency questionnaire by 5,512 M...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Journal of Obesity |
| Online Access: | http://dx.doi.org/10.1155/2014/634587 |
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| _version_ | 1832563758972534784 |
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| author | Patricia A. Metcalf Robert K. R. Scragg Rod Jackson |
| author_facet | Patricia A. Metcalf Robert K. R. Scragg Rod Jackson |
| author_sort | Patricia A. Metcalf |
| collection | DOAJ |
| description | Objective. To examine the association between alcohol consumption and risk of type 2 diabetes mellitus (T2DM) overall and by body mass index. Methods. Cross-sectional study of employed individuals. Daily alcohol intakes were calculated from a self-administered food frequency questionnaire by 5,512 Maori, Pacific Island, and European workers (3,992 men, 1520 women) aged 40 years and above. Results. There were 170 new cases of T2DM. Compared to the group with no alcohol consumption and adjusting for age, sex, and ethnicity, the group consuming alcohol had relative risks of T2DM of 0.23 (95% CI: 0.08, 0.65) in normal weight individuals, 0.38 (0.18, 0.81) in overweight individuals, and 0.99 (0.59, 1.67) in obese individuals. After further adjusting for total cholesterol, HDL-cholesterol, triglycerides, smoking habit, physical activity, socioeconomic status, body mass index, and hypertension, the relative risks of T2DM were 0.16 (0.05, 0.50) in normal weight individuals, 0.43 (0.19, 0.97) in overweight individuals, and 0.92 (0.52, 1.60) in overweight individuals. Across the categories of alcohol consumption, there was an approximate U-shaped relationship for new cases of T2DM. There was no significant association between alcohol consumption and IGT. Conclusions. Alcohol consumption was protective against diagnosis of T2DM in normal and overweight individuals but not in the obese. |
| format | Article |
| id | doaj-art-2cec28ee03f041d290d6bb0083afaf50 |
| institution | Kabale University |
| issn | 2090-0708 2090-0716 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Obesity |
| spelling | doaj-art-2cec28ee03f041d290d6bb0083afaf502025-02-03T01:12:35ZengWileyJournal of Obesity2090-07082090-07162014-01-01201410.1155/2014/634587634587Light to Moderate Alcohol Consumption Is Protective for Type 2 Diabetes Mellitus in Normal Weight and Overweight Individuals but Not the ObesePatricia A. Metcalf0Robert K. R. Scragg1Rod Jackson2Department of Statistics, University of Auckland, Private Bag 92019, Auckland 1142, New ZealandDivision of Epidemiology and Biostatistics, School of Population Health, University of Auckland, Private Bag 92019, Auckland 1142, New ZealandDivision of Epidemiology and Biostatistics, School of Population Health, University of Auckland, Private Bag 92019, Auckland 1142, New ZealandObjective. To examine the association between alcohol consumption and risk of type 2 diabetes mellitus (T2DM) overall and by body mass index. Methods. Cross-sectional study of employed individuals. Daily alcohol intakes were calculated from a self-administered food frequency questionnaire by 5,512 Maori, Pacific Island, and European workers (3,992 men, 1520 women) aged 40 years and above. Results. There were 170 new cases of T2DM. Compared to the group with no alcohol consumption and adjusting for age, sex, and ethnicity, the group consuming alcohol had relative risks of T2DM of 0.23 (95% CI: 0.08, 0.65) in normal weight individuals, 0.38 (0.18, 0.81) in overweight individuals, and 0.99 (0.59, 1.67) in obese individuals. After further adjusting for total cholesterol, HDL-cholesterol, triglycerides, smoking habit, physical activity, socioeconomic status, body mass index, and hypertension, the relative risks of T2DM were 0.16 (0.05, 0.50) in normal weight individuals, 0.43 (0.19, 0.97) in overweight individuals, and 0.92 (0.52, 1.60) in overweight individuals. Across the categories of alcohol consumption, there was an approximate U-shaped relationship for new cases of T2DM. There was no significant association between alcohol consumption and IGT. Conclusions. Alcohol consumption was protective against diagnosis of T2DM in normal and overweight individuals but not in the obese.http://dx.doi.org/10.1155/2014/634587 |
| spellingShingle | Patricia A. Metcalf Robert K. R. Scragg Rod Jackson Light to Moderate Alcohol Consumption Is Protective for Type 2 Diabetes Mellitus in Normal Weight and Overweight Individuals but Not the Obese Journal of Obesity |
| title | Light to Moderate Alcohol Consumption Is Protective for Type 2 Diabetes Mellitus in Normal Weight and Overweight Individuals but Not the Obese |
| title_full | Light to Moderate Alcohol Consumption Is Protective for Type 2 Diabetes Mellitus in Normal Weight and Overweight Individuals but Not the Obese |
| title_fullStr | Light to Moderate Alcohol Consumption Is Protective for Type 2 Diabetes Mellitus in Normal Weight and Overweight Individuals but Not the Obese |
| title_full_unstemmed | Light to Moderate Alcohol Consumption Is Protective for Type 2 Diabetes Mellitus in Normal Weight and Overweight Individuals but Not the Obese |
| title_short | Light to Moderate Alcohol Consumption Is Protective for Type 2 Diabetes Mellitus in Normal Weight and Overweight Individuals but Not the Obese |
| title_sort | light to moderate alcohol consumption is protective for type 2 diabetes mellitus in normal weight and overweight individuals but not the obese |
| url | http://dx.doi.org/10.1155/2014/634587 |
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