Towards Elimination of Mother-to-Child Transmission of HIV: The Impact of a Rapid Results Initiative in Nyanza Province, Kenya
Many HIV-positive pregnant women and infants are still not receiving optimal services, preventing the goal of eliminating mother-to-child transmission (MTCT) and improving maternal child health overall. A Rapid Results Initiative (RRI) approach was utilized to address key challenges in delivery of p...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | AIDS Research and Treatment |
| Online Access: | http://dx.doi.org/10.1155/2012/602120 |
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| author | Lisa L. Dillabaugh Jayne Lewis Kulzer Kevin Owuor Valerie Ndege Arbogast Oyanga Evelyne Ngugi Starley B. Shade Elizabeth Bukusi Craig R. Cohen |
| author_facet | Lisa L. Dillabaugh Jayne Lewis Kulzer Kevin Owuor Valerie Ndege Arbogast Oyanga Evelyne Ngugi Starley B. Shade Elizabeth Bukusi Craig R. Cohen |
| author_sort | Lisa L. Dillabaugh |
| collection | DOAJ |
| description | Many HIV-positive pregnant women and infants are still not receiving optimal services, preventing the goal of eliminating mother-to-child transmission (MTCT) and improving maternal child health overall. A Rapid Results Initiative (RRI) approach was utilized to address key challenges in delivery of prevention of MTCT (PMTCT) services including highly active antiretroviral therapy (HAART) uptake for women and infants. The RRI was conducted between April and June 2011 at 119 health facilities in five districts in Nyanza Province, Kenya. Aggregated site-level data were compared at baseline before the RRI (Oct 2010–Jan 2011), during the RRI, and post-RRI (Jul–Sep 2011) using pre-post cohort analysis. HAART uptake amongst all HIV-positive pregnant women increased by 40% (RR 1.4, 95% CI 1.2–1.7) and continued to improve post-RRI (RR 1.6, 95% CI 1.4–1.8). HAART uptake in HIV-positive infants remained stable (RR 1.1, 95% CI 0.9–1.4) during the RRI and improved by 30% (RR 1.3, 95% CI 1.0–1.6) post-RRI. Significant improvement in PMTCT services can be achieved through introduction of an RRI, which appears to lead to sustained benefits for pregnant HIV-infected women and their infants. |
| format | Article |
| id | doaj-art-2cd53680f6244828a756ce170a62333f |
| institution | Kabale University |
| issn | 2090-1240 2090-1259 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | AIDS Research and Treatment |
| spelling | doaj-art-2cd53680f6244828a756ce170a62333f2025-02-03T06:42:13ZengWileyAIDS Research and Treatment2090-12402090-12592012-01-01201210.1155/2012/602120602120Towards Elimination of Mother-to-Child Transmission of HIV: The Impact of a Rapid Results Initiative in Nyanza Province, KenyaLisa L. Dillabaugh0Jayne Lewis Kulzer1Kevin Owuor2Valerie Ndege3Arbogast Oyanga4Evelyne Ngugi5Starley B. Shade6Elizabeth Bukusi7Craig R. Cohen8Department of Pediatrics, University of California San Francisco, San Francisco, CA, USAFamily AIDS Care and Education Services (FACES), Research, Care and Training Program, Kenya Medical Research Institute, Kisumu, KenyaFamily AIDS Care and Education Services (FACES), Research, Care and Training Program, Kenya Medical Research Institute, Kisumu, KenyaFamily AIDS Care and Education Services (FACES), Research, Care and Training Program, Kenya Medical Research Institute, Kisumu, KenyaFamily AIDS Care and Education Services (FACES), Research, Care and Training Program, Kenya Medical Research Institute, Kisumu, KenyaU.S. Centers for Disease Control and Prevention, Division of Global HIV/AIDS, Nairobi, KenyaFamily AIDS Care and Education Services (FACES), Research, Care and Training Program, Kenya Medical Research Institute, Kisumu, KenyaFamily AIDS Care and Education Services (FACES), Research, Care and Training Program, Kenya Medical Research Institute, Kisumu, KenyaFamily AIDS Care and Education Services (FACES), Research, Care and Training Program, Kenya Medical Research Institute, Kisumu, KenyaMany HIV-positive pregnant women and infants are still not receiving optimal services, preventing the goal of eliminating mother-to-child transmission (MTCT) and improving maternal child health overall. A Rapid Results Initiative (RRI) approach was utilized to address key challenges in delivery of prevention of MTCT (PMTCT) services including highly active antiretroviral therapy (HAART) uptake for women and infants. The RRI was conducted between April and June 2011 at 119 health facilities in five districts in Nyanza Province, Kenya. Aggregated site-level data were compared at baseline before the RRI (Oct 2010–Jan 2011), during the RRI, and post-RRI (Jul–Sep 2011) using pre-post cohort analysis. HAART uptake amongst all HIV-positive pregnant women increased by 40% (RR 1.4, 95% CI 1.2–1.7) and continued to improve post-RRI (RR 1.6, 95% CI 1.4–1.8). HAART uptake in HIV-positive infants remained stable (RR 1.1, 95% CI 0.9–1.4) during the RRI and improved by 30% (RR 1.3, 95% CI 1.0–1.6) post-RRI. Significant improvement in PMTCT services can be achieved through introduction of an RRI, which appears to lead to sustained benefits for pregnant HIV-infected women and their infants.http://dx.doi.org/10.1155/2012/602120 |
| spellingShingle | Lisa L. Dillabaugh Jayne Lewis Kulzer Kevin Owuor Valerie Ndege Arbogast Oyanga Evelyne Ngugi Starley B. Shade Elizabeth Bukusi Craig R. Cohen Towards Elimination of Mother-to-Child Transmission of HIV: The Impact of a Rapid Results Initiative in Nyanza Province, Kenya AIDS Research and Treatment |
| title | Towards Elimination of Mother-to-Child Transmission of HIV: The Impact of a Rapid Results Initiative in Nyanza Province, Kenya |
| title_full | Towards Elimination of Mother-to-Child Transmission of HIV: The Impact of a Rapid Results Initiative in Nyanza Province, Kenya |
| title_fullStr | Towards Elimination of Mother-to-Child Transmission of HIV: The Impact of a Rapid Results Initiative in Nyanza Province, Kenya |
| title_full_unstemmed | Towards Elimination of Mother-to-Child Transmission of HIV: The Impact of a Rapid Results Initiative in Nyanza Province, Kenya |
| title_short | Towards Elimination of Mother-to-Child Transmission of HIV: The Impact of a Rapid Results Initiative in Nyanza Province, Kenya |
| title_sort | towards elimination of mother to child transmission of hiv the impact of a rapid results initiative in nyanza province kenya |
| url | http://dx.doi.org/10.1155/2012/602120 |
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