Decreased protein activator of interferon induced protein kinase (PRKRA) involved in menopause-related cholesterol metabolic disorders by regulating cholesterol biosynthesis

Abstract Background Menopause-related cholesterol metabolic disorders pose a global health concern, but the underlying mechanism is unclear. PRKRA was identified as a potential regulator of cholesterol metabolism in an exome-wide association study. Our prior research revealed a decrease in PRKRA exp...

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Bibliographic Details
Main Authors: Le Xu, Jian Xu, Wanting Shi, Sa Zhang, Ting Guo, Shien Zou
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Lipids in Health and Disease
Subjects:
Online Access:https://doi.org/10.1186/s12944-025-02575-w
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