Twisted gastrulation, a BMP antagonist, exacerbates podocyte injury.

Twisted gastrulation, a BMP antagonist, exacerbates podocyte injury.

Podocyte injury is the first step in the progression of glomerulosclerosis. Previous studies have demonstrated the beneficial effect of bone morphogenetic protein 7 (Bmp7) in podocyte injury and the existence of native Bmp signaling in podocytes. Local activity of Bmp7 is controlled by cell-type spe...

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Main Authors: Sachiko Yamada, Jin Nakamura, Misako Asada, Masayuki Takase, Taiji Matsusaka, Taku Iguchi, Ryo Yamada, Mari Tanaka, Atsuko Y Higashi, Tomohiko Okuda, Nariaki Asada, Atsushi Fukatsu, Hiroshi Kawachi, Daniel Graf, Eri Muso, Toru Kita, Takeshi Kimura, Ira Pastan, Aris N Economides, Motoko Yanagita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089135&type=printable
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