Competitive exclusion in an infection-age structured vector-host epidemic model
The competitive exclusion principle means that the strain with the largest reproduction number persists while eliminating all other strains with suboptimal reproduction numbers. In this paper, we extend the competitive exclusion principle to a multi-strain vector-borne epidemic model with age-since-...
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AIMS Press
2017-07-01
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| author | Yanxia Dang Zhipeng Qiu Xuezhi Li |
| author_facet | Yanxia Dang Zhipeng Qiu Xuezhi Li |
| author_sort | Yanxia Dang |
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| description | The competitive exclusion principle means that the strain with the largest reproduction number persists while eliminating all other strains with suboptimal reproduction numbers. In this paper, we extend the competitive exclusion principle to a multi-strain vector-borne epidemic model with age-since-infection. The model includes both incubation age of the exposed hosts and infection age of the infectious hosts, both of which describe the different removal rates in the latent period and the variable infectiousness in the infectious period, respectively. The formulas for the reproduction numbers $\mathcal R^j_0$ of strain $j,j=1,2,···, n$ , are obtained from the biological meanings of the model. The strain $j$ can not invade the system if $\mathcal R^j_0 \lt 1$ , and the disease free equilibrium is globally asymptotically stable if $\max_j\{\mathcal R^j_0\} \lt 1$ . If $\mathcal R^{j_0}_0 \gt 1$ , then a single-strain equilibrium $\mathcal{E}_{j_0}$ exists, and the single strain equilibrium is locally asymptotically stable when $\mathcal R^{j_0}_0 \gt 1$ and $\mathcal R^{j_0}_0 \gt \mathcal R^{j}_0,j≠ j_0$ . Finally, by using a Lyapunov function, sufficient conditions are further established for the global asymptotical stability of the single-strain equilibrium corresponding to strain $j_0$ , which means strain $j_0$ eliminates all other stains as long as $\mathcal R^{j}_0/\mathcal R^{j_0}_0 \lt b_j/b_{j_0} \lt 1,j≠ j_0$ , where $b_j$ denotes the probability of a given susceptible vector being transmitted by an infected host with strain $j$ . |
| format | Article |
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| institution | Kabale University |
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| spelling | doaj-art-2cb68499f3374a6582fd819975689ab52025-01-24T02:39:54ZengAIMS PressMathematical Biosciences and Engineering1551-00182017-07-0114490193110.3934/mbe.2017048Competitive exclusion in an infection-age structured vector-host epidemic modelYanxia Dang0Zhipeng Qiu1Xuezhi Li2Department of Public Education, Zhumadian Vocational and Technical College, Zhumadian 463000, ChinaSchool of Science, Nanjing University of Science and Technology, Nanjing 210094, ChinaDepartment of Mathematics and Physics, Anyang Institute of Technology, Anyang 455000, ChinaThe competitive exclusion principle means that the strain with the largest reproduction number persists while eliminating all other strains with suboptimal reproduction numbers. In this paper, we extend the competitive exclusion principle to a multi-strain vector-borne epidemic model with age-since-infection. The model includes both incubation age of the exposed hosts and infection age of the infectious hosts, both of which describe the different removal rates in the latent period and the variable infectiousness in the infectious period, respectively. The formulas for the reproduction numbers $\mathcal R^j_0$ of strain $j,j=1,2,···, n$ , are obtained from the biological meanings of the model. The strain $j$ can not invade the system if $\mathcal R^j_0 \lt 1$ , and the disease free equilibrium is globally asymptotically stable if $\max_j\{\mathcal R^j_0\} \lt 1$ . If $\mathcal R^{j_0}_0 \gt 1$ , then a single-strain equilibrium $\mathcal{E}_{j_0}$ exists, and the single strain equilibrium is locally asymptotically stable when $\mathcal R^{j_0}_0 \gt 1$ and $\mathcal R^{j_0}_0 \gt \mathcal R^{j}_0,j≠ j_0$ . Finally, by using a Lyapunov function, sufficient conditions are further established for the global asymptotical stability of the single-strain equilibrium corresponding to strain $j_0$ , which means strain $j_0$ eliminates all other stains as long as $\mathcal R^{j}_0/\mathcal R^{j_0}_0 \lt b_j/b_{j_0} \lt 1,j≠ j_0$ , where $b_j$ denotes the probability of a given susceptible vector being transmitted by an infected host with strain $j$ .https://www.aimspress.com/article/doi/10.3934/mbe.2017048age-structurecompetitive exclusionglobal stabilityvector-borne diseaselyapunov function |
| spellingShingle | Yanxia Dang Zhipeng Qiu Xuezhi Li Competitive exclusion in an infection-age structured vector-host epidemic model Mathematical Biosciences and Engineering age-structure competitive exclusion global stability vector-borne disease lyapunov function |
| title | Competitive exclusion in an infection-age structured vector-host epidemic model |
| title_full | Competitive exclusion in an infection-age structured vector-host epidemic model |
| title_fullStr | Competitive exclusion in an infection-age structured vector-host epidemic model |
| title_full_unstemmed | Competitive exclusion in an infection-age structured vector-host epidemic model |
| title_short | Competitive exclusion in an infection-age structured vector-host epidemic model |
| title_sort | competitive exclusion in an infection age structured vector host epidemic model |
| topic | age-structure competitive exclusion global stability vector-borne disease lyapunov function |
| url | https://www.aimspress.com/article/doi/10.3934/mbe.2017048 |
| work_keys_str_mv | AT yanxiadang competitiveexclusioninaninfectionagestructuredvectorhostepidemicmodel AT zhipengqiu competitiveexclusioninaninfectionagestructuredvectorhostepidemicmodel AT xuezhili competitiveexclusioninaninfectionagestructuredvectorhostepidemicmodel |