Posttransplant Lymphoproliferative Disorder in a Patient with Worsening Ascites after Liver Transplantation
Posttransplant lymphoproliferative disorder (PTLD) is a spectrum of diseases that involves abnormal lymphoid and/or plasmacytic proliferation in patients with solid organ or hematopoietic cell transplantation. It is a condition with a low incidence of 3.5–4.3% in liver transplant (LT) recipients. Th...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2017/7247438 |
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| _version_ | 1832551520299646976 |
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| author | Harsh D. Patel Moises I. Nevah Rubin |
| author_facet | Harsh D. Patel Moises I. Nevah Rubin |
| author_sort | Harsh D. Patel |
| collection | DOAJ |
| description | Posttransplant lymphoproliferative disorder (PTLD) is a spectrum of diseases that involves abnormal lymphoid and/or plasmacytic proliferation in patients with solid organ or hematopoietic cell transplantation. It is a condition with a low incidence of 3.5–4.3% in liver transplant (LT) recipients. This case involves a 63-year-old male with history of LT for chronic HCV induced cirrhosis who presented with abdominal distension related to worsening ascites. Cytological ascitic fluid analysis revealed EBV (+) malignant cells without a malignant focal point on imaging. Diagnosis of monomorphic PTLD with primary effusion lymphoma-like morphology and immunophenotype was established. This case highlights the complexity in diagnosis, different diagnostic modalities, and rare clinical presentations of PTLD. |
| format | Article |
| id | doaj-art-2cae7e8c93214143b0bbb65b3be3929e |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-2cae7e8c93214143b0bbb65b3be3929e2025-02-03T06:01:12ZengWileyCase Reports in Hematology2090-65602090-65792017-01-01201710.1155/2017/72474387247438Posttransplant Lymphoproliferative Disorder in a Patient with Worsening Ascites after Liver TransplantationHarsh D. Patel0Moises I. Nevah Rubin1McGovern Medical School, Department of Internal Medicine, The University of Texas Health Science Center at Houston, 6431 Fannin St., Suite MSB 1.134, Houston, TX 77030, USAMcGovern Medical School, Department of Gastroenterology, Transplant and Advanced Hepatology, The University of Texas Health Science Center at Houston, 6431 Fannin St., Suite MSB 1.134, Houston, TX 77030, USAPosttransplant lymphoproliferative disorder (PTLD) is a spectrum of diseases that involves abnormal lymphoid and/or plasmacytic proliferation in patients with solid organ or hematopoietic cell transplantation. It is a condition with a low incidence of 3.5–4.3% in liver transplant (LT) recipients. This case involves a 63-year-old male with history of LT for chronic HCV induced cirrhosis who presented with abdominal distension related to worsening ascites. Cytological ascitic fluid analysis revealed EBV (+) malignant cells without a malignant focal point on imaging. Diagnosis of monomorphic PTLD with primary effusion lymphoma-like morphology and immunophenotype was established. This case highlights the complexity in diagnosis, different diagnostic modalities, and rare clinical presentations of PTLD.http://dx.doi.org/10.1155/2017/7247438 |
| spellingShingle | Harsh D. Patel Moises I. Nevah Rubin Posttransplant Lymphoproliferative Disorder in a Patient with Worsening Ascites after Liver Transplantation Case Reports in Hematology |
| title | Posttransplant Lymphoproliferative Disorder in a Patient with Worsening Ascites after Liver Transplantation |
| title_full | Posttransplant Lymphoproliferative Disorder in a Patient with Worsening Ascites after Liver Transplantation |
| title_fullStr | Posttransplant Lymphoproliferative Disorder in a Patient with Worsening Ascites after Liver Transplantation |
| title_full_unstemmed | Posttransplant Lymphoproliferative Disorder in a Patient with Worsening Ascites after Liver Transplantation |
| title_short | Posttransplant Lymphoproliferative Disorder in a Patient with Worsening Ascites after Liver Transplantation |
| title_sort | posttransplant lymphoproliferative disorder in a patient with worsening ascites after liver transplantation |
| url | http://dx.doi.org/10.1155/2017/7247438 |
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