Laparoscopic versus open left hemicolectomy for left-sided colon cancer: protocol for a systematic review and meta-analysis
Introduction Laparoscopic colectomy has been widely used clinically due to its minimally invasive advantages, and many studies have also demonstrated its safety and efficacy. However, the efficacy of laparoscopic left hemicolectomy remains unclear due to the differences in pathogenesis and surgical...
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BMJ Publishing Group
2022-06-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/6/e062216.full |
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| author | Yang Yang Yong Wang Lie Yang Qiang Du Jianhao Zhang Xueting Liu |
| author_facet | Yang Yang Yong Wang Lie Yang Qiang Du Jianhao Zhang Xueting Liu |
| author_sort | Yang Yang |
| collection | DOAJ |
| description | Introduction Laparoscopic colectomy has been widely used clinically due to its minimally invasive advantages, and many studies have also demonstrated its safety and efficacy. However, the efficacy of laparoscopic left hemicolectomy remains unclear due to the differences in pathogenesis and surgical details between left and right colon cancers. Therefore, we plan to conduct a systematic review and meta-analysis to investigate whether laparoscopic techniques can be safely used in left hemicolectomy.Method and analysis This meta-analysis protocol will be completed and reported according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols guidelines. A systematic search was performed for all articles related to laparoscopic left hemicolectomy in PubMed, Web of Science, Medline, EMBASE and the Cochrane Library from inception to 5 November 2021. Article screening and data extraction were performed independently by two authors and cross-checked after completion. The literature to be included will use corresponding tools for bias risk assessment. Subgroup analyses and sensitivity analyses will be used to explore potential heterogeneity.Ethics and dissemination Because this systematic review is based on studies with published results and does not involve intervention in patients, no ethical review is required. The results of this study will be published in a peer-reviewed journal.PROSPERO registration number CRD42022291526. |
| format | Article |
| id | doaj-art-2cad0c63d0df42ccb10cdf9cb1da2e52 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-2cad0c63d0df42ccb10cdf9cb1da2e522025-01-24T03:40:14ZengBMJ Publishing GroupBMJ Open2044-60552022-06-0112610.1136/bmjopen-2022-062216Laparoscopic versus open left hemicolectomy for left-sided colon cancer: protocol for a systematic review and meta-analysisYang Yang0Yong Wang1Lie Yang2Qiang Du3Jianhao Zhang4Xueting Liu5Department of Gastrointestinal Surgery, Sichuan University West China Hospital, Chengdu, Sichuan, China1 Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China1 Department of Gastrointestinal Surgery, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, ChinaDepartment of Gastrointestinal Surgery, Sichuan University West China Hospital, Chengdu, Sichuan, ChinaDepartment of Gastrointestinal Surgery, Sichuan University West China Hospital, Chengdu, Sichuan, ChinaDepartment of Evidence-Based Medicine and Clinical Epidemiology, Sichuan University West China Hospital, Chengdu, Sichuan, ChinaIntroduction Laparoscopic colectomy has been widely used clinically due to its minimally invasive advantages, and many studies have also demonstrated its safety and efficacy. However, the efficacy of laparoscopic left hemicolectomy remains unclear due to the differences in pathogenesis and surgical details between left and right colon cancers. Therefore, we plan to conduct a systematic review and meta-analysis to investigate whether laparoscopic techniques can be safely used in left hemicolectomy.Method and analysis This meta-analysis protocol will be completed and reported according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols guidelines. A systematic search was performed for all articles related to laparoscopic left hemicolectomy in PubMed, Web of Science, Medline, EMBASE and the Cochrane Library from inception to 5 November 2021. Article screening and data extraction were performed independently by two authors and cross-checked after completion. The literature to be included will use corresponding tools for bias risk assessment. Subgroup analyses and sensitivity analyses will be used to explore potential heterogeneity.Ethics and dissemination Because this systematic review is based on studies with published results and does not involve intervention in patients, no ethical review is required. The results of this study will be published in a peer-reviewed journal.PROSPERO registration number CRD42022291526.https://bmjopen.bmj.com/content/12/6/e062216.full |
| spellingShingle | Yang Yang Yong Wang Lie Yang Qiang Du Jianhao Zhang Xueting Liu Laparoscopic versus open left hemicolectomy for left-sided colon cancer: protocol for a systematic review and meta-analysis BMJ Open |
| title | Laparoscopic versus open left hemicolectomy for left-sided colon cancer: protocol for a systematic review and meta-analysis |
| title_full | Laparoscopic versus open left hemicolectomy for left-sided colon cancer: protocol for a systematic review and meta-analysis |
| title_fullStr | Laparoscopic versus open left hemicolectomy for left-sided colon cancer: protocol for a systematic review and meta-analysis |
| title_full_unstemmed | Laparoscopic versus open left hemicolectomy for left-sided colon cancer: protocol for a systematic review and meta-analysis |
| title_short | Laparoscopic versus open left hemicolectomy for left-sided colon cancer: protocol for a systematic review and meta-analysis |
| title_sort | laparoscopic versus open left hemicolectomy for left sided colon cancer protocol for a systematic review and meta analysis |
| url | https://bmjopen.bmj.com/content/12/6/e062216.full |
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