Respiratory Consequences of Mild-to-Moderate Obesity: Impact on Exercise Performance in Health and in Chronic Obstructive Pulmonary Disease
In many parts of the world, the prevalence of obesity is increasing at an alarming rate. The association between obesity, multiple comorbidities, and increased mortality is now firmly established in many epidemiological studies. However, the link between obesity and exercise intolerance is less well...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Pulmonary Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/818925 |
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| author | Denis E. O'Donnell Conor D. J. O'Donnell Katherine A. Webb Jordan A. Guenette |
| author_facet | Denis E. O'Donnell Conor D. J. O'Donnell Katherine A. Webb Jordan A. Guenette |
| author_sort | Denis E. O'Donnell |
| collection | DOAJ |
| description | In many parts of the world, the prevalence of obesity is increasing at an alarming rate. The association between obesity, multiple comorbidities, and increased mortality is now firmly established in many epidemiological studies. However, the link between obesity and exercise intolerance is less well studied and is the focus of this paper. Although exercise limitation is likely to be multifactorial in obesity, it is widely believed that the respiratory mechanical constraints and the attendant dyspnea are important contributors. In this paper, we examined the evidence that critical ventilatory constraint is a proximate source of exercise limitation in individuals with mild-to-moderate obesity. We first reviewed existing information on exercise performance, including ventilatory and perceptual response patterns, in obese individuals who are otherwise healthy. We then considered the impact of obesity in patients with preexisting respiratory mechanical abnormalities due to chronic obstructive pulmonary disease (COPD), with particular reference to the effect on dyspnea and exercise performance. Our main conclusion, based on the existing and rather sparse literature on the subject, is that abnormalities of dynamic respiratory mechanics are not likely to be the dominant source of dyspnea and exercise intolerance in otherwise healthy individuals or in patients with COPD with mild-to-moderate obesity. |
| format | Article |
| id | doaj-art-2c99aa516eaa4e4880d3c8ac68ef057d |
| institution | OA Journals |
| issn | 2090-1836 2090-1844 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pulmonary Medicine |
| spelling | doaj-art-2c99aa516eaa4e4880d3c8ac68ef057d2025-08-20T02:24:04ZengWileyPulmonary Medicine2090-18362090-18442012-01-01201210.1155/2012/818925818925Respiratory Consequences of Mild-to-Moderate Obesity: Impact on Exercise Performance in Health and in Chronic Obstructive Pulmonary DiseaseDenis E. O'Donnell0Conor D. J. O'Donnell1Katherine A. Webb2Jordan A. Guenette3Respiratory Investigation Unit, Department of Medicine, Queen's University and Kingston General Hospital, 102 Stuart Street, Kingston, ON, K7L 2V6, CanadaRespiratory Investigation Unit, Department of Medicine, Queen's University and Kingston General Hospital, 102 Stuart Street, Kingston, ON, K7L 2V6, CanadaRespiratory Investigation Unit, Department of Medicine, Queen's University and Kingston General Hospital, 102 Stuart Street, Kingston, ON, K7L 2V6, CanadaRespiratory Investigation Unit, Department of Medicine, Queen's University and Kingston General Hospital, 102 Stuart Street, Kingston, ON, K7L 2V6, CanadaIn many parts of the world, the prevalence of obesity is increasing at an alarming rate. The association between obesity, multiple comorbidities, and increased mortality is now firmly established in many epidemiological studies. However, the link between obesity and exercise intolerance is less well studied and is the focus of this paper. Although exercise limitation is likely to be multifactorial in obesity, it is widely believed that the respiratory mechanical constraints and the attendant dyspnea are important contributors. In this paper, we examined the evidence that critical ventilatory constraint is a proximate source of exercise limitation in individuals with mild-to-moderate obesity. We first reviewed existing information on exercise performance, including ventilatory and perceptual response patterns, in obese individuals who are otherwise healthy. We then considered the impact of obesity in patients with preexisting respiratory mechanical abnormalities due to chronic obstructive pulmonary disease (COPD), with particular reference to the effect on dyspnea and exercise performance. Our main conclusion, based on the existing and rather sparse literature on the subject, is that abnormalities of dynamic respiratory mechanics are not likely to be the dominant source of dyspnea and exercise intolerance in otherwise healthy individuals or in patients with COPD with mild-to-moderate obesity.http://dx.doi.org/10.1155/2012/818925 |
| spellingShingle | Denis E. O'Donnell Conor D. J. O'Donnell Katherine A. Webb Jordan A. Guenette Respiratory Consequences of Mild-to-Moderate Obesity: Impact on Exercise Performance in Health and in Chronic Obstructive Pulmonary Disease Pulmonary Medicine |
| title | Respiratory Consequences of Mild-to-Moderate Obesity: Impact on Exercise Performance in Health and in Chronic Obstructive Pulmonary Disease |
| title_full | Respiratory Consequences of Mild-to-Moderate Obesity: Impact on Exercise Performance in Health and in Chronic Obstructive Pulmonary Disease |
| title_fullStr | Respiratory Consequences of Mild-to-Moderate Obesity: Impact on Exercise Performance in Health and in Chronic Obstructive Pulmonary Disease |
| title_full_unstemmed | Respiratory Consequences of Mild-to-Moderate Obesity: Impact on Exercise Performance in Health and in Chronic Obstructive Pulmonary Disease |
| title_short | Respiratory Consequences of Mild-to-Moderate Obesity: Impact on Exercise Performance in Health and in Chronic Obstructive Pulmonary Disease |
| title_sort | respiratory consequences of mild to moderate obesity impact on exercise performance in health and in chronic obstructive pulmonary disease |
| url | http://dx.doi.org/10.1155/2012/818925 |
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