Computational Fluid Dynamics Investigation on Transplantation Anastomoses
A surgical technique, known as hepatic artery patch, is applied in the anastomosis of the hepatic artery to minimize complications such as hepatic artery thrombosis (HAT). This surgical technique is used when there is a diameter size difference in the two connected arteries. Computational fluid dyna...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
AIDIC Servizi S.r.l.
2025-07-01
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| Series: | Chemical Engineering Transactions |
| Online Access: | https://www.cetjournal.it/index.php/cet/article/view/15440 |
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| Summary: | A surgical technique, known as hepatic artery patch, is applied in the anastomosis of the hepatic artery to minimize complications such as hepatic artery thrombosis (HAT). This surgical technique is used when there is a diameter size difference in the two connected arteries. Computational fluid dynamics (CFD) is a tool for solving problems including various phenomena (e.g., fluid flow, mass transfer, heat transfer) (Raman et al., 2018). Moreover, CFD has a wide range of applications from turbomachinery design and aerodynamics of aircrafts to food industry, drug delivery and even more (Raman et al., 2018; Kiparissides et al., 2018). There is limited data from the viewpoint of CFD studying the HAT problem and how it can be reduced or prevented. Herein, the hepatic artery anastomosis using hepatic artery patch is studied. For this, the geometric characteristics, such as the diameter of the connection that the patch should have, in relation to the blood inlet and outlet artery (i.e., the recipient’s blood vessel diameter, the donor’s blood vessel diameter), are studied. In addition, pulsatile flow with various assumed heart rates inside and outside the normal range are considered together with a Carreau model for blood rheology (Zouggari et al., 2018). The CFD solver, ANSYS, has been used to generate the simulation results. It is known that ANSYS is appropriate to simulate complex geometries (Papadimitriou et al., 2011). Solutions are obtained over a span of at least three flow pulses. In the literature wall shear stress and blood velocity are associated with thrombosis and plaque formation (Reorowicz et al., 2022). The simulation results are compared with clinical studies from the literature on the risk of thrombosis. |
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| ISSN: | 2283-9216 |