Compartment Syndrome as a Result of Systemic Capillary Leak Syndrome

Objective. To describe a single case of Systemic Capillary Leak Syndrome (SCLS) with a rare complication of compartment syndrome. Patient. Our patient is a 57-year-old male, referred to our hospital due to polycythemia (hemoglobin (Hgb) of 220 g/L), hypotension, acute renal failure, and bilateral ca...

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Main Authors: Kwadwo Kyeremanteng, Gianni D’Egidio, Cynthia Wan, Alan Baxter, Hans Rosenberg
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2016/4206397
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author Kwadwo Kyeremanteng
Gianni D’Egidio
Cynthia Wan
Alan Baxter
Hans Rosenberg
author_facet Kwadwo Kyeremanteng
Gianni D’Egidio
Cynthia Wan
Alan Baxter
Hans Rosenberg
author_sort Kwadwo Kyeremanteng
collection DOAJ
description Objective. To describe a single case of Systemic Capillary Leak Syndrome (SCLS) with a rare complication of compartment syndrome. Patient. Our patient is a 57-year-old male, referred to our hospital due to polycythemia (hemoglobin (Hgb) of 220 g/L), hypotension, acute renal failure, and bilateral calf pain. Measurements and Main Results. The patient required bilateral forearm, thigh, and calf fasciotomies during his ICU stay and continuous renal replacement therapy was instituted following onset of acute renal failure and oliguria. Ongoing hemodynamic (Norepinephrine and Milrinone infusion) and respiratory (ventilator) support in the ICU was provided until resolution of intravascular fluid extravasation. Conclusions. SCLS is an extremely rare disorder characterized by unexplained episodic capillary hyperpermeability, which causes shift of volume and protein from the intravascular space to the interstitial space. Patients present with significant hypotension, hemoconcentration, hypovolemia, and oliguria. Severe edema results from leakage of fluid and proteins into tissue. The most important part of treatment is maintaining stable hemodynamics, ruling out other causes of shock and diligent monitoring for complications. Awareness of the clinical syndrome with the rare complication of compartment syndrome may help guide investigations and diagnoses of these critically ill patients.
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spelling doaj-art-2c30cbb543d4415884ae4808665c8d032025-02-03T01:01:48ZengWileyCase Reports in Critical Care2090-64202090-64392016-01-01201610.1155/2016/42063974206397Compartment Syndrome as a Result of Systemic Capillary Leak SyndromeKwadwo Kyeremanteng0Gianni D’Egidio1Cynthia Wan2Alan Baxter3Hans Rosenberg4The Ottawa Hospital, Ottawa, ON, CanadaThe Ottawa Hospital, Ottawa, ON, CanadaSchool of Psychology, The University of Ottawa, Ottawa, ON, CanadaThe Ottawa Hospital, Ottawa, ON, CanadaThe Ottawa Hospital, Ottawa, ON, CanadaObjective. To describe a single case of Systemic Capillary Leak Syndrome (SCLS) with a rare complication of compartment syndrome. Patient. Our patient is a 57-year-old male, referred to our hospital due to polycythemia (hemoglobin (Hgb) of 220 g/L), hypotension, acute renal failure, and bilateral calf pain. Measurements and Main Results. The patient required bilateral forearm, thigh, and calf fasciotomies during his ICU stay and continuous renal replacement therapy was instituted following onset of acute renal failure and oliguria. Ongoing hemodynamic (Norepinephrine and Milrinone infusion) and respiratory (ventilator) support in the ICU was provided until resolution of intravascular fluid extravasation. Conclusions. SCLS is an extremely rare disorder characterized by unexplained episodic capillary hyperpermeability, which causes shift of volume and protein from the intravascular space to the interstitial space. Patients present with significant hypotension, hemoconcentration, hypovolemia, and oliguria. Severe edema results from leakage of fluid and proteins into tissue. The most important part of treatment is maintaining stable hemodynamics, ruling out other causes of shock and diligent monitoring for complications. Awareness of the clinical syndrome with the rare complication of compartment syndrome may help guide investigations and diagnoses of these critically ill patients.http://dx.doi.org/10.1155/2016/4206397
spellingShingle Kwadwo Kyeremanteng
Gianni D’Egidio
Cynthia Wan
Alan Baxter
Hans Rosenberg
Compartment Syndrome as a Result of Systemic Capillary Leak Syndrome
Case Reports in Critical Care
title Compartment Syndrome as a Result of Systemic Capillary Leak Syndrome
title_full Compartment Syndrome as a Result of Systemic Capillary Leak Syndrome
title_fullStr Compartment Syndrome as a Result of Systemic Capillary Leak Syndrome
title_full_unstemmed Compartment Syndrome as a Result of Systemic Capillary Leak Syndrome
title_short Compartment Syndrome as a Result of Systemic Capillary Leak Syndrome
title_sort compartment syndrome as a result of systemic capillary leak syndrome
url http://dx.doi.org/10.1155/2016/4206397
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AT giannidegidio compartmentsyndromeasaresultofsystemiccapillaryleaksyndrome
AT cynthiawan compartmentsyndromeasaresultofsystemiccapillaryleaksyndrome
AT alanbaxter compartmentsyndromeasaresultofsystemiccapillaryleaksyndrome
AT hansrosenberg compartmentsyndromeasaresultofsystemiccapillaryleaksyndrome