Santa-maria is a glial phagocytic receptor that acts with SIMU to recognize and engulf apoptotic neurons

Santa-maria is a glial phagocytic receptor that acts with SIMU to recognize and engulf apoptotic neurons

Summary: The elimination of superfluous neurons via apoptosis and subsequent glial phagocytosis is crucial for the development of the central nervous system (CNS). In Drosophila, two glial phagocytic receptors, six-microns-under (SIMU) and Draper, mediate the phagocytosis of apoptotic neurons during...

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Bibliographic Details
Main Authors: Reut Hilu-Dadia, Aseel Ghanem, Shelly Vogelesang, Malak Ayoub, Ketty Hakim-Mishnaevski, Estee Kurant
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Cell Reports
Subjects:
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724015523
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