Research status of clearing indoxyl sulfate by targeting intestinal flora
Indoxyl sulfate （IS）， as a typical uremia toxin metabolized by intestinal microorganism， plays an important role in the occurrence and development of chronic kidney disease （CKD） and its related complications. With the proposal of "entero-renal axis" theory， it has shown that intestinal fl...
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| Format: | Article |
| Language: | zho |
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Editorial Department of Journal of Clinical Nephrology
2022-06-01
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| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.06.011 |
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| author | Chen Shuang Wang Xiu-li Zhang Meng-fan Zhang Hai-song |
| author_facet | Chen Shuang Wang Xiu-li Zhang Meng-fan Zhang Hai-song |
| author_sort | Chen Shuang |
| collection | DOAJ |
| description | Indoxyl sulfate （IS）， as a typical uremia toxin metabolized by intestinal microorganism， plays an important role in the occurrence and development of chronic kidney disease （CKD） and its related complications. With the proposal of "entero-renal axis" theory， it has shown that intestinal flora imbalance may elevate the level of IS level， accelerate disease progression and lead to a poor prognosis in CKD patients. This review summarized the latest methods of targeting intestinal flora for clearing IS. |
| format | Article |
| id | doaj-art-2bf5219e5fb44aed8b12d67d9f6f9e3c |
| institution | OA Journals |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2022-06-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-2bf5219e5fb44aed8b12d67d9f6f9e3c2025-08-20T02:16:10ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902022-06-012250751028234910Research status of clearing indoxyl sulfate by targeting intestinal floraChen ShuangWang Xiu-liZhang Meng-fanZhang Hai-songIndoxyl sulfate （IS）， as a typical uremia toxin metabolized by intestinal microorganism， plays an important role in the occurrence and development of chronic kidney disease （CKD） and its related complications. With the proposal of "entero-renal axis" theory， it has shown that intestinal flora imbalance may elevate the level of IS level， accelerate disease progression and lead to a poor prognosis in CKD patients. This review summarized the latest methods of targeting intestinal flora for clearing IS.http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.06.011Indoxyl sulfateIntestinal flora dysregulationChronic kidney diseaseMicroecologics |
| spellingShingle | Chen Shuang Wang Xiu-li Zhang Meng-fan Zhang Hai-song Research status of clearing indoxyl sulfate by targeting intestinal flora Linchuang shenzangbing zazhi Indoxyl sulfate Intestinal flora dysregulation Chronic kidney disease Microecologics |
| title | Research status of clearing indoxyl sulfate by targeting intestinal flora |
| title_full | Research status of clearing indoxyl sulfate by targeting intestinal flora |
| title_fullStr | Research status of clearing indoxyl sulfate by targeting intestinal flora |
| title_full_unstemmed | Research status of clearing indoxyl sulfate by targeting intestinal flora |
| title_short | Research status of clearing indoxyl sulfate by targeting intestinal flora |
| title_sort | research status of clearing indoxyl sulfate by targeting intestinal flora |
| topic | Indoxyl sulfate Intestinal flora dysregulation Chronic kidney disease Microecologics |
| url | http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.06.011 |
| work_keys_str_mv | AT chenshuang researchstatusofclearingindoxylsulfatebytargetingintestinalflora AT wangxiuli researchstatusofclearingindoxylsulfatebytargetingintestinalflora AT zhangmengfan researchstatusofclearingindoxylsulfatebytargetingintestinalflora AT zhanghaisong researchstatusofclearingindoxylsulfatebytargetingintestinalflora |