Notch3 Targeting: A Novel Weapon against Ovarian Cancer Stem Cells

Notch signaling is frequently activated in ovarian cancer (OC) and contributes to the proliferation and survival of cultured OC cells as well as to tumor formation and angiogenesis in xenograft models. Several studies demonstrate that Notch3 expression renders cancer cells more resistant to carbopla...

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Bibliographic Details
Main Authors: Simona Ceccarelli, Francesca Megiorni, Diana Bellavia, Cinzia Marchese, Isabella Screpanti, Saula Checquolo
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2019/6264931
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