Research advances in Pimpinella thellungiana: Nutrients, bioactive compounds, and functional properties benefitting livestock
Growth retardation affects the health and production of livestock, while overexertion can cause sudden cardiac arrest. Both cases are considered to be metabolic disorders and are detrimental to livestock production. Effective measures for relieving or treating these disorders are scarce. However, Pi...
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KeAi Communications Co., Ltd.
2025-03-01
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| Series: | Animal Nutrition |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405654524001598 |
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| author | Shuxian Zhang Minglu Yang Tao Xu Qiongxian Yan Allan Degen Xiaoling Zhou |
| author_facet | Shuxian Zhang Minglu Yang Tao Xu Qiongxian Yan Allan Degen Xiaoling Zhou |
| author_sort | Shuxian Zhang |
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| description | Growth retardation affects the health and production of livestock, while overexertion can cause sudden cardiac arrest. Both cases are considered to be metabolic disorders and are detrimental to livestock production. Effective measures for relieving or treating these disorders are scarce. However, Pimpinella thellungiana H. Wolff (P. thellungiana), a medicinal herb, has been reported to relieve growth retardation and overexertion in ethnopharmacological clinical trials. This paper summarizes and classifies a total of 106 bioactive compounds that were isolated and identified from P. thellungiana, including flavonoids, simple phenylpropanoids, coumarins, volatile compounds, and simple polyphenols, and discusses its pharmaceutical benefits, including its growth-promoting, antioxidant, anti-inflammatory, anti-atherosclerotic, and hepatoprotective properties. The nutrition, metabolism, biological activities, and pharmacological effects of the principal compounds of P. thellungiana in livestock are reviewed, as well as their potential molecular targets and metabolic signaling pathways in which these compounds are involved. However, the pharmacological and toxicological effects of some compounds have not been well documented, and further investigations of the bioactive compounds are needed. Such studies are crucial for the development of natural drugs or feed additives from P. thellungiana to alleviate growth retardation and mitigate injuries from overexertion in livestock. |
| format | Article |
| id | doaj-art-2be1df13a87a417387d47c5541dbdc01 |
| institution | Kabale University |
| issn | 2405-6545 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Animal Nutrition |
| spelling | doaj-art-2be1df13a87a417387d47c5541dbdc012025-02-06T05:12:28ZengKeAi Communications Co., Ltd.Animal Nutrition2405-65452025-03-0120239248Research advances in Pimpinella thellungiana: Nutrients, bioactive compounds, and functional properties benefitting livestockShuxian Zhang0Minglu Yang1Tao Xu2Qiongxian Yan3Allan Degen4Xiaoling Zhou5College of Animal Science and Technology, Tarim University, Key Laboratory of Livestock and Forage Resources Utilization Around Tarim in Ministry of Agriculture and Rural Affairs, Alaer 843300, ChinaCollege of Agriculture, Tarim University, Alaer 843300, ChinaCollege of Animal Science and Technology, Tarim University, Key Laboratory of Livestock and Forage Resources Utilization Around Tarim in Ministry of Agriculture and Rural Affairs, Alaer 843300, ChinaInstitute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha 410125, ChinaDesert Animal Adaptations and Husbandry, Wyler Department of Dryland Agriculture, Blaustein Institutes for Desert Research, Ben-Gurion University of the Negev, Beer Sheva 8410500, IsraelCollege of Animal Science and Technology, Tarim University, Key Laboratory of Livestock and Forage Resources Utilization Around Tarim in Ministry of Agriculture and Rural Affairs, Alaer 843300, China; Corresponding author.Growth retardation affects the health and production of livestock, while overexertion can cause sudden cardiac arrest. Both cases are considered to be metabolic disorders and are detrimental to livestock production. Effective measures for relieving or treating these disorders are scarce. However, Pimpinella thellungiana H. Wolff (P. thellungiana), a medicinal herb, has been reported to relieve growth retardation and overexertion in ethnopharmacological clinical trials. This paper summarizes and classifies a total of 106 bioactive compounds that were isolated and identified from P. thellungiana, including flavonoids, simple phenylpropanoids, coumarins, volatile compounds, and simple polyphenols, and discusses its pharmaceutical benefits, including its growth-promoting, antioxidant, anti-inflammatory, anti-atherosclerotic, and hepatoprotective properties. The nutrition, metabolism, biological activities, and pharmacological effects of the principal compounds of P. thellungiana in livestock are reviewed, as well as their potential molecular targets and metabolic signaling pathways in which these compounds are involved. However, the pharmacological and toxicological effects of some compounds have not been well documented, and further investigations of the bioactive compounds are needed. Such studies are crucial for the development of natural drugs or feed additives from P. thellungiana to alleviate growth retardation and mitigate injuries from overexertion in livestock.http://www.sciencedirect.com/science/article/pii/S2405654524001598Pimpinella thellungiana H. WolffNutrition and metabolismBioactive compound and functionPharmacological valueGrowth retardationOverexertion |
| spellingShingle | Shuxian Zhang Minglu Yang Tao Xu Qiongxian Yan Allan Degen Xiaoling Zhou Research advances in Pimpinella thellungiana: Nutrients, bioactive compounds, and functional properties benefitting livestock Animal Nutrition Pimpinella thellungiana H. Wolff Nutrition and metabolism Bioactive compound and function Pharmacological value Growth retardation Overexertion |
| title | Research advances in Pimpinella thellungiana: Nutrients, bioactive compounds, and functional properties benefitting livestock |
| title_full | Research advances in Pimpinella thellungiana: Nutrients, bioactive compounds, and functional properties benefitting livestock |
| title_fullStr | Research advances in Pimpinella thellungiana: Nutrients, bioactive compounds, and functional properties benefitting livestock |
| title_full_unstemmed | Research advances in Pimpinella thellungiana: Nutrients, bioactive compounds, and functional properties benefitting livestock |
| title_short | Research advances in Pimpinella thellungiana: Nutrients, bioactive compounds, and functional properties benefitting livestock |
| title_sort | research advances in pimpinella thellungiana nutrients bioactive compounds and functional properties benefitting livestock |
| topic | Pimpinella thellungiana H. Wolff Nutrition and metabolism Bioactive compound and function Pharmacological value Growth retardation Overexertion |
| url | http://www.sciencedirect.com/science/article/pii/S2405654524001598 |
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