Methylation of Promoter Regions of Genes of the Human Intrauterine Renin Angiotensin System and Their Expression
The intrauterine renin angiotensin system (RAS) is implicated in placentation and labour onset. Here we investigate whether promoter methylation of RAS genes changes with gestation or labour and if it affects gene expression. Early gestation amnion and placenta were studied, as were term amnion, dec...
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| Main Authors: | Shane D. Sykes, Carolyn Mitchell, Kirsty G. Pringle, Yu Wang, Tamas Zakar, Eugenie R. Lumbers |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2015/459818 |
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