Harnessing the Power of Traditional Chinese Medicine in Cancer Treatment: The Role of Nanocarriers

Ziyu Fu,1 Shengmei Wang,1 Xin Zhou,1 Linqi Ouyang,1 Zhen Chen,1 Guiming Deng1,2 1The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, 410007, People’s Republic of China; 2The second Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, 410005, People’s Republic o...

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Main Authors: Fu Z, Wang S, Zhou X, Ouyang L, Chen Z, Deng G
Format: Article
Language:English
Published: Dove Medical Press 2025-03-01
Series:International Journal of Nanomedicine
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Online Access:https://www.dovepress.com/harnessing-the-power-of-traditional-chinese-medicine-in-cancer-treatme-peer-reviewed-fulltext-article-IJN
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author Fu Z
Wang S
Zhou X
Ouyang L
Chen Z
Deng G
author_facet Fu Z
Wang S
Zhou X
Ouyang L
Chen Z
Deng G
author_sort Fu Z
collection DOAJ
description Ziyu Fu,1 Shengmei Wang,1 Xin Zhou,1 Linqi Ouyang,1 Zhen Chen,1 Guiming Deng1,2 1The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, 410007, People’s Republic of China; 2The second Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, 410005, People’s Republic of ChinaCorrespondence: Zhen Chen; Guiming Deng, Email 1018793145@qq.com; guimingd1004@163.comAbstract: For centuries, traditional Chinese medicine (TCM) has had certain advantages in the treatment of tumors. However, due to their poor water solubility, low bioavailability and potential toxicity, their effective delivery to target sites can be a major challenge. Nanocarriers based on the active ingredients of TCM, such as liposomes, polymer nanoparticles, inorganic nanoparticles, and organic/inorganic nanohybrids, are a promising strategy to improve the delivery of TCM, resulting in higher therapeutic outcomes and fewer side effects. Therefore, this article intends to review the application of Chinese medicine nano preparation in tumor. Firstly, we introduce the classification and synthesis of nanometer preparations of Chinese medicine. The second part mainly introduces the different responses of TCM nano-preparations in the course of treatment to introduce how TCM nano-preparations play a role in anti-tumor therapy. The third part focuses on Different response modes of Chinese medicine nano preparations in tumor therapy. The fourth part elucidates the application of Chinese medicine nano preparations in the treatment of cancer. Finally, the research direction to be explored in related fields is put forward.Keywords: traditional Chinese medicine, tumor, nanodelivery system, tumor therapy
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spelling doaj-art-2bc5e9843b4d4e7fad5ff239a10160052025-08-20T02:53:03ZengDove Medical PressInternational Journal of Nanomedicine1178-20132025-03-01Volume 2031473174101108Harnessing the Power of Traditional Chinese Medicine in Cancer Treatment: The Role of NanocarriersFu ZWang SZhou XOuyang LChen ZDeng GZiyu Fu,1 Shengmei Wang,1 Xin Zhou,1 Linqi Ouyang,1 Zhen Chen,1 Guiming Deng1,2 1The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, 410007, People’s Republic of China; 2The second Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, 410005, People’s Republic of ChinaCorrespondence: Zhen Chen; Guiming Deng, Email 1018793145@qq.com; guimingd1004@163.comAbstract: For centuries, traditional Chinese medicine (TCM) has had certain advantages in the treatment of tumors. However, due to their poor water solubility, low bioavailability and potential toxicity, their effective delivery to target sites can be a major challenge. Nanocarriers based on the active ingredients of TCM, such as liposomes, polymer nanoparticles, inorganic nanoparticles, and organic/inorganic nanohybrids, are a promising strategy to improve the delivery of TCM, resulting in higher therapeutic outcomes and fewer side effects. Therefore, this article intends to review the application of Chinese medicine nano preparation in tumor. Firstly, we introduce the classification and synthesis of nanometer preparations of Chinese medicine. The second part mainly introduces the different responses of TCM nano-preparations in the course of treatment to introduce how TCM nano-preparations play a role in anti-tumor therapy. The third part focuses on Different response modes of Chinese medicine nano preparations in tumor therapy. The fourth part elucidates the application of Chinese medicine nano preparations in the treatment of cancer. Finally, the research direction to be explored in related fields is put forward.Keywords: traditional Chinese medicine, tumor, nanodelivery system, tumor therapyhttps://www.dovepress.com/harnessing-the-power-of-traditional-chinese-medicine-in-cancer-treatme-peer-reviewed-fulltext-article-IJNtraditional chinese medicinetumornanodelivery systemtumor therapy
spellingShingle Fu Z
Wang S
Zhou X
Ouyang L
Chen Z
Deng G
Harnessing the Power of Traditional Chinese Medicine in Cancer Treatment: The Role of Nanocarriers
International Journal of Nanomedicine
traditional chinese medicine
tumor
nanodelivery system
tumor therapy
title Harnessing the Power of Traditional Chinese Medicine in Cancer Treatment: The Role of Nanocarriers
title_full Harnessing the Power of Traditional Chinese Medicine in Cancer Treatment: The Role of Nanocarriers
title_fullStr Harnessing the Power of Traditional Chinese Medicine in Cancer Treatment: The Role of Nanocarriers
title_full_unstemmed Harnessing the Power of Traditional Chinese Medicine in Cancer Treatment: The Role of Nanocarriers
title_short Harnessing the Power of Traditional Chinese Medicine in Cancer Treatment: The Role of Nanocarriers
title_sort harnessing the power of traditional chinese medicine in cancer treatment the role of nanocarriers
topic traditional chinese medicine
tumor
nanodelivery system
tumor therapy
url https://www.dovepress.com/harnessing-the-power-of-traditional-chinese-medicine-in-cancer-treatme-peer-reviewed-fulltext-article-IJN
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