Comparative analysis of isoxazoline activity on human and canine GABA receptors expressed in Xenopus oocytes
Abstract Background Isoxazolines, including sarolaner, lotilaner, afoxolaner and fluralaner, are a class of ectoparasiticides that target gamma-aminobutyric acid receptors (GABARs) in insects and acari. However, their potential action on mammalian GABARs has not been extensively compared. Methods Th...
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| Main Authors: | Heinz Sager, Anouk Sarr, Emmanuelle Kuntz, Lucien Rufener |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-06-01
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| Series: | Parasites & Vectors |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13071-025-06847-3 |
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