An Efficient Green Procedure for Synthesis of Some Fluorinated Curcumin Analogues Catalyzed by Calcium Oxide under Microwave Irradiation and Its Antibacterial Evaluation
A series of fluorine substituted curcumin analogues have been synthesized in a cheaper and greener method using calcium oxide as catalyst under microwave irradiation. All the synthesized compounds have been characterized by FT-IR, MS, elemental analysis, and 1H and 13C NMR spectroscopic techniques a...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2013/640936 |
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| author | S. Elavarasan D. Bhakiaraj T. Elavarasan M. Gopalakrishnan |
| author_facet | S. Elavarasan D. Bhakiaraj T. Elavarasan M. Gopalakrishnan |
| author_sort | S. Elavarasan |
| collection | DOAJ |
| description | A series of fluorine substituted curcumin analogues have been synthesized in a cheaper and greener method using calcium oxide as catalyst under microwave irradiation. All the synthesized compounds have been characterized by FT-IR, MS, elemental analysis, and 1H and 13C NMR spectroscopic techniques and screened for antibacterial activities against Staphylococcus aureus, β-Heamolytic streptococcus, Shigella flexneri, Vibrio cholerae, Pseudomonas aeruginosa, and Klebsiella pneumonia. All the synthesized compounds are showing good zone of inhibition against the tested bacterial strains. |
| format | Article |
| id | doaj-art-2bb9b6ba8f8e40e7844952bfa0ad9270 |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-2bb9b6ba8f8e40e7844952bfa0ad92702025-02-03T07:24:44ZengWileyJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/640936640936An Efficient Green Procedure for Synthesis of Some Fluorinated Curcumin Analogues Catalyzed by Calcium Oxide under Microwave Irradiation and Its Antibacterial EvaluationS. Elavarasan0D. Bhakiaraj1T. Elavarasan2M. Gopalakrishnan3Synthetic Organic Chemistry Laboratory, Department of Chemistry, Annamalai University, Annamalainagar, Tamil Nadu 608 002, IndiaSynthetic Organic Chemistry Laboratory, Department of Chemistry, Annamalai University, Annamalainagar, Tamil Nadu 608 002, IndiaSynthetic Organic Chemistry Laboratory, Department of Chemistry, Annamalai University, Annamalainagar, Tamil Nadu 608 002, IndiaSynthetic Organic Chemistry Laboratory, Department of Chemistry, Annamalai University, Annamalainagar, Tamil Nadu 608 002, IndiaA series of fluorine substituted curcumin analogues have been synthesized in a cheaper and greener method using calcium oxide as catalyst under microwave irradiation. All the synthesized compounds have been characterized by FT-IR, MS, elemental analysis, and 1H and 13C NMR spectroscopic techniques and screened for antibacterial activities against Staphylococcus aureus, β-Heamolytic streptococcus, Shigella flexneri, Vibrio cholerae, Pseudomonas aeruginosa, and Klebsiella pneumonia. All the synthesized compounds are showing good zone of inhibition against the tested bacterial strains.http://dx.doi.org/10.1155/2013/640936 |
| spellingShingle | S. Elavarasan D. Bhakiaraj T. Elavarasan M. Gopalakrishnan An Efficient Green Procedure for Synthesis of Some Fluorinated Curcumin Analogues Catalyzed by Calcium Oxide under Microwave Irradiation and Its Antibacterial Evaluation Journal of Chemistry |
| title | An Efficient Green Procedure for Synthesis of Some Fluorinated Curcumin Analogues Catalyzed by Calcium Oxide under Microwave Irradiation and Its Antibacterial Evaluation |
| title_full | An Efficient Green Procedure for Synthesis of Some Fluorinated Curcumin Analogues Catalyzed by Calcium Oxide under Microwave Irradiation and Its Antibacterial Evaluation |
| title_fullStr | An Efficient Green Procedure for Synthesis of Some Fluorinated Curcumin Analogues Catalyzed by Calcium Oxide under Microwave Irradiation and Its Antibacterial Evaluation |
| title_full_unstemmed | An Efficient Green Procedure for Synthesis of Some Fluorinated Curcumin Analogues Catalyzed by Calcium Oxide under Microwave Irradiation and Its Antibacterial Evaluation |
| title_short | An Efficient Green Procedure for Synthesis of Some Fluorinated Curcumin Analogues Catalyzed by Calcium Oxide under Microwave Irradiation and Its Antibacterial Evaluation |
| title_sort | efficient green procedure for synthesis of some fluorinated curcumin analogues catalyzed by calcium oxide under microwave irradiation and its antibacterial evaluation |
| url | http://dx.doi.org/10.1155/2013/640936 |
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