Performance and usability evaluation of three LDH-based malaria rapid diagnostic tests in Kédougou, Senegal

Performance and usability evaluation of three LDH-based malaria rapid diagnostic tests in Kédougou, Senegal

Abstract Background The emergence of Plasmodium falciparum (Pf) parasites with deleted histidine-rich protein 2 and 3 (hrp2/hrp3) genes threatens the performance of HRP2-based malaria rapid diagnostic tests (RDTs). RDTs targeting Pf lactate dehydrogenase (LDH) may address current product limitations...

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Main Authors: Babacar Souleymane Sambe, Stephanie Zobrist, William Sheahan, Divya Soni, Aissatou Diagne, Ibrahima Sarr, Arona Sabene Diatta, Serigne Ousmane Mbacke Diaw, Allison Golden, Hannah Slater, Ihn Kyung Jang, Nerie Roa, Sampa Pal, Fatoumata Diene Sarr, Joseph Faye, Inès Vigan-Womas, Yakou Dieye, Moustapha Cisse, Gonzalo J. Domingo, Makhtar Niang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Parasites & Vectors
Subjects:
Malaria
Diagnosis
Rapid diagnostic test
Lactate dehydrogenase
Histidine rich protein 2
Online Access:https://doi.org/10.1186/s13071-025-06914-9
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