Marburg variant of multiple sclerosis: A young women case report
Marburg disease (malignant multiple sclerosis, MS) is a rare, acute MS variant, predominantly occurring among young adults. Because it is characterized by rarity, high morbidity and mortality rates, the disease needs to be further characterized, and the experience of the physicians play a role in tr...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-03-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043324013505 |
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| author | Mohammed Alaa Jameel Wameth Alaa Jamel Alaa Jameel Hasan Riyam Amer Hammood Alkhuzaie |
| author_facet | Mohammed Alaa Jameel Wameth Alaa Jamel Alaa Jameel Hasan Riyam Amer Hammood Alkhuzaie |
| author_sort | Mohammed Alaa Jameel |
| collection | DOAJ |
| description | Marburg disease (malignant multiple sclerosis, MS) is a rare, acute MS variant, predominantly occurring among young adults. Because it is characterized by rarity, high morbidity and mortality rates, the disease needs to be further characterized, and the experience of the physicians play a role in treatment regimens. We report the case of a 15-years-old female presenting with progressive weakness over the limbs, hyperreflexia and loss of sensation by physical examination, lab tests and radiological investigations (MRI). After treatment, nonimprovement was recognized by symptoms review after IV corticosteroids, Gabapentin and Clonazepam intake during a clinical visit. IV corticosteroids, Gabapentin and Clonazepam are not sufficient treatment for Marburg's variant of multiple sclerosis disease. Therefore, aggressive therapies can be used to further suppress the inflammatory process to prevent further neurological damage. |
| format | Article |
| id | doaj-art-2b9c966465d747f19e017c987ff449cc |
| institution | Kabale University |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-2b9c966465d747f19e017c987ff449cc2025-01-18T05:04:01ZengElsevierRadiology Case Reports1930-04332025-03-0120315591563Marburg variant of multiple sclerosis: A young women case reportMohammed Alaa Jameel0Wameth Alaa Jamel1Alaa Jameel Hasan2Riyam Amer Hammood Alkhuzaie3Royal Blackburn Teaching Hospital, East Lancashire Hospitals NHS Trust, East Lancashire, England, UK; Corresponding author.Department of Plastic Surgery, Al-Wasity Teaching Hospital, Baghdad Al-Russafa Health Directorate, Baghdad, IraqThi-Qar University, College of Medicine, Department of Surgery, Nasiriyah, Dhi Qar Governorate, IraqEmergency Department, Baghdad Medical City, Baghdad, IraqMarburg disease (malignant multiple sclerosis, MS) is a rare, acute MS variant, predominantly occurring among young adults. Because it is characterized by rarity, high morbidity and mortality rates, the disease needs to be further characterized, and the experience of the physicians play a role in treatment regimens. We report the case of a 15-years-old female presenting with progressive weakness over the limbs, hyperreflexia and loss of sensation by physical examination, lab tests and radiological investigations (MRI). After treatment, nonimprovement was recognized by symptoms review after IV corticosteroids, Gabapentin and Clonazepam intake during a clinical visit. IV corticosteroids, Gabapentin and Clonazepam are not sufficient treatment for Marburg's variant of multiple sclerosis disease. Therefore, aggressive therapies can be used to further suppress the inflammatory process to prevent further neurological damage.http://www.sciencedirect.com/science/article/pii/S1930043324013505Multiple sclerosisMarburg variantDemyelinating disorder |
| spellingShingle | Mohammed Alaa Jameel Wameth Alaa Jamel Alaa Jameel Hasan Riyam Amer Hammood Alkhuzaie Marburg variant of multiple sclerosis: A young women case report Radiology Case Reports Multiple sclerosis Marburg variant Demyelinating disorder |
| title | Marburg variant of multiple sclerosis: A young women case report |
| title_full | Marburg variant of multiple sclerosis: A young women case report |
| title_fullStr | Marburg variant of multiple sclerosis: A young women case report |
| title_full_unstemmed | Marburg variant of multiple sclerosis: A young women case report |
| title_short | Marburg variant of multiple sclerosis: A young women case report |
| title_sort | marburg variant of multiple sclerosis a young women case report |
| topic | Multiple sclerosis Marburg variant Demyelinating disorder |
| url | http://www.sciencedirect.com/science/article/pii/S1930043324013505 |
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