Cardiac magnetic resonance markers of pre-clinical hypertrophic and dilated cardiomyopathy in genetic variant carriers

Cardiac magnetic resonance markers of pre-clinical hypertrophic and dilated cardiomyopathy in genetic variant carriers

Abstract Background Patients with hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) exhibit structural and functional cardiac abnormalities. We aimed to identify imaging biomarkers for pre-clinical cardiomyopathy in healthy participants carrying cardiomyopathy-associated variants (G...

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Main Authors: Philip M. Croon, Marion van Vugt, Cornelis P. Allaart, Bram Ruijsink, Perry M. Elliott, Folkert W. Asselbergs, Rohan Khera, Connie R. Bezzina, Michiel Winter, A. Floriaan Schmidt
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Medicine
Subjects:
Dilated cardiomyopathy
Cardiac magnetic resonance
Hypertrophic cardiomyopathy
Whole exome sequencing
Genetics
Online Access:https://doi.org/10.1186/s12916-025-04226-4
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