Insights into the molecular underlying mechanisms and therapeutic potential of endoplasmic reticulum stress in sensorineural hearing loss

Insights into the molecular underlying mechanisms and therapeutic potential of endoplasmic reticulum stress in sensorineural hearing loss

Sensorineural hearing loss (SNHL) is characterized by a compromised cochlear perception of sound waves. Major risk factors for SNHL include genetic mutations, exposure to noise, ototoxic medications, and the aging process. Previous research has demonstrated that inflammation, oxidative stress, apopt...

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Bibliographic Details
Main Authors: Guanzhen Li, Huiming Yang, Peiyuan Zhang, Yan Guo, Lili Yuan, Shujiao Xu, Yingxue Yuan, Huabao Xiong, Haiyan Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
sensorineural hearing loss
endoplasmic reticulum stress
unfolded protein response
oxidative stress
apoptosis
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2024.1443401/full
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https://www.frontiersin.org/articles/10.3389/fnmol.2024.1443401/full

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