The investigation of molecular epidemiological characteristics and resistance mechanism of tigecycline resistant Klebsiella pneumoniae from a large teaching hospital in southwest China, Chongqing

The investigation of molecular epidemiological characteristics and resistance mechanism of tigecycline resistant Klebsiella pneumoniae from a large teaching hospital in southwest China, Chongqing

BackgroundKlebsiella pneumoniae is one of the main pathogens of nosocomial infection, among which carbapenems can be used for multidrug-resistant Klebsiella pneumoniae. However, in the past decade, the resistance rate of carbapenem-resistant Klebsiella pneumoniae has increased yearly. Tigecycline ha...

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Bibliographic Details
Main Authors: Yuqiong Li, Shiyu Tang, Qi Han, Peiwen Xia, Tingting Si, Yuanyuan Song, Yun Xia
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
resistance mechanism
Klebsiella pneumoniae
tigecycline-resistance
tet(A)
RND efflux pump
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1540967/full
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