The role of extra-familial factors in adolescence for the association between out-of-home care and adult psychiatric disorders-A birth cohort study.

<h4>Background</h4>Psychiatric disorders are a substantial public health concern, and childhood adversity a well-known risk factor for it. Investigating gender differences in vulnerability and resilience processes following out-of-home care (OHC) as proxy for childhood adversity can help...

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Main Authors: Lisa Bornscheuer, Evelina Landstedt, Ylva B Almquist
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0318231
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author Lisa Bornscheuer
Evelina Landstedt
Ylva B Almquist
author_facet Lisa Bornscheuer
Evelina Landstedt
Ylva B Almquist
author_sort Lisa Bornscheuer
collection DOAJ
description <h4>Background</h4>Psychiatric disorders are a substantial public health concern, and childhood adversity a well-known risk factor for it. Investigating gender differences in vulnerability and resilience processes following out-of-home care (OHC) as proxy for childhood adversity can help map opportunities for the prevention of psychiatric disorders.<h4>Methods</h4>We followed a large birth cohort for psychiatric disorders (anxiety, depression, and self-harm, and substance misuse) between age 25-62 years, comparing individuals with and without OHC experience. We investigated different extra-familial risk and resources factors following OHC via gender-stratified mediation and moderation analyses to approximate risk accumulation (vulnerability processes) and buffers of risk (resilience processes).<h4>Results</h4>OHC is prospectively associated with psychiatric disorders in adulthood. Lower school grades, delinquency, and early parenthood are mediators of the association, with the exception of education in girls in relation to anxiety, depression, and self-harm, and early parenthood in boys in relation to substance misuse. Number of best friends moderates OHC experience in boys, and there is a trend for higher educational achievement to also act as buffer, even though this trend was not statistically significant. Leisure time activities did not act as buffer.<h4>Conclusion</h4>Vulnerability and resilience processes after childhood adversity are gendered: Risk accumulation runs via delinquency and poorer educational outcomes in boys more than in girls, while early parenthood is a more dominant risk factor in girls. Having more best friends and higher grades may act as buffer, especially in boys.
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spelling doaj-art-2b4deae1c0f84b19a032476fbf2197522025-02-05T05:31:58ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01201e031823110.1371/journal.pone.0318231The role of extra-familial factors in adolescence for the association between out-of-home care and adult psychiatric disorders-A birth cohort study.Lisa BornscheuerEvelina LandstedtYlva B Almquist<h4>Background</h4>Psychiatric disorders are a substantial public health concern, and childhood adversity a well-known risk factor for it. Investigating gender differences in vulnerability and resilience processes following out-of-home care (OHC) as proxy for childhood adversity can help map opportunities for the prevention of psychiatric disorders.<h4>Methods</h4>We followed a large birth cohort for psychiatric disorders (anxiety, depression, and self-harm, and substance misuse) between age 25-62 years, comparing individuals with and without OHC experience. We investigated different extra-familial risk and resources factors following OHC via gender-stratified mediation and moderation analyses to approximate risk accumulation (vulnerability processes) and buffers of risk (resilience processes).<h4>Results</h4>OHC is prospectively associated with psychiatric disorders in adulthood. Lower school grades, delinquency, and early parenthood are mediators of the association, with the exception of education in girls in relation to anxiety, depression, and self-harm, and early parenthood in boys in relation to substance misuse. Number of best friends moderates OHC experience in boys, and there is a trend for higher educational achievement to also act as buffer, even though this trend was not statistically significant. Leisure time activities did not act as buffer.<h4>Conclusion</h4>Vulnerability and resilience processes after childhood adversity are gendered: Risk accumulation runs via delinquency and poorer educational outcomes in boys more than in girls, while early parenthood is a more dominant risk factor in girls. Having more best friends and higher grades may act as buffer, especially in boys.https://doi.org/10.1371/journal.pone.0318231
spellingShingle Lisa Bornscheuer
Evelina Landstedt
Ylva B Almquist
The role of extra-familial factors in adolescence for the association between out-of-home care and adult psychiatric disorders-A birth cohort study.
PLoS ONE
title The role of extra-familial factors in adolescence for the association between out-of-home care and adult psychiatric disorders-A birth cohort study.
title_full The role of extra-familial factors in adolescence for the association between out-of-home care and adult psychiatric disorders-A birth cohort study.
title_fullStr The role of extra-familial factors in adolescence for the association between out-of-home care and adult psychiatric disorders-A birth cohort study.
title_full_unstemmed The role of extra-familial factors in adolescence for the association between out-of-home care and adult psychiatric disorders-A birth cohort study.
title_short The role of extra-familial factors in adolescence for the association between out-of-home care and adult psychiatric disorders-A birth cohort study.
title_sort role of extra familial factors in adolescence for the association between out of home care and adult psychiatric disorders a birth cohort study
url https://doi.org/10.1371/journal.pone.0318231
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