Hepatitis C Infection and Periodontal Disease: Is there a Common Immunological Link?
Hepatitis C virus (HCV) infections could have an important impact on the oral health status of patients, favoring conditions such as periodontal disease and oral cancer. The review of the existing scientific literature written in English was performed, searching for oral and periodontal manifestatio...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2018/8720101 |
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| _version_ | 1832554208318980096 |
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| author | Dorin Nicolae Gheorghe Liliana Foia Vasilica Toma Amelia Surdu Elena Herascu Dora Maria Popescu Petra Surlin Cristin Constantin Vere Ion Rogoveanu |
| author_facet | Dorin Nicolae Gheorghe Liliana Foia Vasilica Toma Amelia Surdu Elena Herascu Dora Maria Popescu Petra Surlin Cristin Constantin Vere Ion Rogoveanu |
| author_sort | Dorin Nicolae Gheorghe |
| collection | DOAJ |
| description | Hepatitis C virus (HCV) infections could have an important impact on the oral health status of patients, favoring conditions such as periodontal disease and oral cancer. The review of the existing scientific literature written in English was performed, searching for oral and periodontal manifestations of HCV infection and its impact on the oral fluids. HCV infection can determine direct extrahepatic manifestations at the oral and periodontal level including oral lichen planus, Sjögren-like sialadenitis, and oral cancer. The changes caused by the infection in the subjects’ immune system, diet, and lifestyle can facilitate the development of oral conditions such as periodontal disease. Important changes also occur in the composition of the infected patients’ saliva and gingival fluid. HCV-infected patients need to be carefully monitored in terms of oral health since the infection with the virus can result in oral complications. The cellular and molecular particularities of the gingival fluid of HCV-infected patients can answer some questions regarding its impact upon periodontium impairment and whether this refers to a possible bidirectional relationship, with hepatic biomarker adjustments being induced by the periodontal patients’ inflammatory status. |
| format | Article |
| id | doaj-art-2b43671b66714e22ae89d3f309a9d977 |
| institution | Kabale University |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-2b43671b66714e22ae89d3f309a9d9772025-02-03T05:52:09ZengWileyJournal of Immunology Research2314-88612314-71562018-01-01201810.1155/2018/87201018720101Hepatitis C Infection and Periodontal Disease: Is there a Common Immunological Link?Dorin Nicolae Gheorghe0Liliana Foia1Vasilica Toma2Amelia Surdu3Elena Herascu4Dora Maria Popescu5Petra Surlin6Cristin Constantin Vere7Ion Rogoveanu8Department of Periodontology, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, 2 Petru Rares street, 200349 Craiova, RomaniaDepartment of Biochemistry, University of Medicine and Pharmacy “Grigore T. Popa”, 16 Universitatii street, 700115 Iasi, RomaniaDepartment of Oral Surgery, University of Medicine and Pharmacy “Grigore T. Popa”, 16 Universitatii street, 700115 Iasi, RomaniaDepartment of Implantology, University of Medicine and Pharmacy “Grigore T. Popa”, 16 Universitatii street, 700115 Iasi, RomaniaDepartment of Gastroenterology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 2 Petru Rares street, 200349 Craiova, RomaniaDepartment of Periodontology, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, 2 Petru Rares street, 200349 Craiova, RomaniaDepartment of Periodontology, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, 2 Petru Rares street, 200349 Craiova, RomaniaDepartment of Gastroenterology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 2 Petru Rares street, 200349 Craiova, RomaniaDepartment of Gastroenterology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 2 Petru Rares street, 200349 Craiova, RomaniaHepatitis C virus (HCV) infections could have an important impact on the oral health status of patients, favoring conditions such as periodontal disease and oral cancer. The review of the existing scientific literature written in English was performed, searching for oral and periodontal manifestations of HCV infection and its impact on the oral fluids. HCV infection can determine direct extrahepatic manifestations at the oral and periodontal level including oral lichen planus, Sjögren-like sialadenitis, and oral cancer. The changes caused by the infection in the subjects’ immune system, diet, and lifestyle can facilitate the development of oral conditions such as periodontal disease. Important changes also occur in the composition of the infected patients’ saliva and gingival fluid. HCV-infected patients need to be carefully monitored in terms of oral health since the infection with the virus can result in oral complications. The cellular and molecular particularities of the gingival fluid of HCV-infected patients can answer some questions regarding its impact upon periodontium impairment and whether this refers to a possible bidirectional relationship, with hepatic biomarker adjustments being induced by the periodontal patients’ inflammatory status.http://dx.doi.org/10.1155/2018/8720101 |
| spellingShingle | Dorin Nicolae Gheorghe Liliana Foia Vasilica Toma Amelia Surdu Elena Herascu Dora Maria Popescu Petra Surlin Cristin Constantin Vere Ion Rogoveanu Hepatitis C Infection and Periodontal Disease: Is there a Common Immunological Link? Journal of Immunology Research |
| title | Hepatitis C Infection and Periodontal Disease: Is there a Common Immunological Link? |
| title_full | Hepatitis C Infection and Periodontal Disease: Is there a Common Immunological Link? |
| title_fullStr | Hepatitis C Infection and Periodontal Disease: Is there a Common Immunological Link? |
| title_full_unstemmed | Hepatitis C Infection and Periodontal Disease: Is there a Common Immunological Link? |
| title_short | Hepatitis C Infection and Periodontal Disease: Is there a Common Immunological Link? |
| title_sort | hepatitis c infection and periodontal disease is there a common immunological link |
| url | http://dx.doi.org/10.1155/2018/8720101 |
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