Molecular characterisation of influenza B virus from the 2017/18 season in primary models of the human lung reveals improved adaptation to the lower respiratory tract

Molecular characterisation of influenza B virus from the 2017/18 season in primary models of the human lung reveals improved adaptation to the lower respiratory tract

The 2017/18 influenza season was characterized by unusual high numbers of severe infections and hospitalizations. Instead of influenza A viruses, this season was dominated by infections with influenza B viruses of the Yamagata lineage. While this IBV/Yam dominance was associated with a vaccine misma...

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Bibliographic Details
Main Authors: Duygu Merve Çalışkan, Sriram Kumar, Saskia Hinse, Klaus Schughart, Rainer Wiewrodt, Stefan Fischer, Vera Krueger, Karsten Wiebe, Peter Barth, Alexander Mellmann, Stephan Ludwig, Linda Brunotte
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Emerging Microbes and Infections
Subjects:
Influenza B virus
human lung explants
lung organoids
cell tropism
innate immune response
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2024.2402868
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