Mosquitocidal efficacy and pharmacokinetics of single-dose ivermectin versus three-day dose regimen for malaria vector control compared with albendazole and no treatment: An open-label randomized controlled trial

Mosquitocidal efficacy and pharmacokinetics of single-dose ivermectin versus three-day dose regimen for malaria vector control compared with albendazole and no treatment: An open-label randomized controlled trial

Objectives: When malaria vectors consume ivermectin in a blood meal, their survival probability decreases, potentially reducing malaria transmission during mass drug administrations. However, questions remain regarding the optimal dosing. This study aimed to compare the mosquitocidal effect and phar...

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Main Authors: Yvonne Kamau, Mercy Tuwei, Caroline Wanjiku, Kelly Ominde, Mwanajuma Ngama, Jonathan Karisa, Lawrence Babu, Martha Muturi, Mwaganyuma Mwatasa, Jane Adetifa, Charlotte Kern, Urs Duthaler, Felix Hammann, Regina Rabinovich, Carlos Chaccour, Marta Ferreira Maia
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:International Journal of Infectious Diseases
Subjects:
Anopheles gambiae
Malaria
Ivermectin
Endectocides
Vector control
Pharmacokinetics
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971224003072
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