Systematic metabolic engineering of Yarrowia lipolytica for efficient production of phytohormone abscisic acid

Systematic metabolic engineering of Yarrowia lipolytica for efficient production of phytohormone abscisic acid

Abscisic acid (ABA) is an important phytohormone with diverse applications. It currently relies on the fermentation of Botrytis cinerea, which suffers from limited availability of genetic engineering tools. Here, Yarrowia lipolytica was engineered to enable de novo biosynthesis of ABA. To overcome t...

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Bibliographic Details
Main Authors: Mei-Li Sun, Ziyun Zou, Lu Lin, Rodrigo Ledesma-Amaro, Kaifeng Wang, Xiao-Jun Ji
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-03-01
Series:Synthetic and Systems Biotechnology
Subjects:
Abscisic acid
Phytohormone
Sesquiterpene
Yarrowia lipolytica
P450 enzymes
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X24001340
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