Antimicrobial Resistance within Host: A Population Dynamics View
To study the relationship between antimicrobial resistance and the concentration of antibiotics, a competitive population dynamical model is proposed between the susceptible strain and the resistant strain with antibiotic exposure. The strict mathematical analysis is performed, and the results indic...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
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| Series: | Abstract and Applied Analysis |
| Online Access: | http://dx.doi.org/10.1155/2014/173952 |
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| _version_ | 1832564737753219072 |
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| author | Chunji Huang Aijun Fan |
| author_facet | Chunji Huang Aijun Fan |
| author_sort | Chunji Huang |
| collection | DOAJ |
| description | To study the relationship between antimicrobial resistance and the concentration of antibiotics, a competitive population dynamical model is proposed between the susceptible strain and the resistant strain with antibiotic exposure. The strict mathematical analysis is performed, and the results indicate that long-term high strength antibiotic treatment and prevention can induce the extinction of susceptible strain. Thus, the prescribed dose of antibiotics must be strictly controlled during the treatment and prevention of the infections in clinics. |
| format | Article |
| id | doaj-art-2b2da550f29a4f76946f2de668493513 |
| institution | Kabale University |
| issn | 1085-3375 1687-0409 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Abstract and Applied Analysis |
| spelling | doaj-art-2b2da550f29a4f76946f2de6684935132025-02-03T01:10:18ZengWileyAbstract and Applied Analysis1085-33751687-04092014-01-01201410.1155/2014/173952173952Antimicrobial Resistance within Host: A Population Dynamics ViewChunji Huang0Aijun Fan1Xinqiao Hospital, Third Military Medical University, Chongqing 400037, ChinaChongqing Research Center for Information and Automation Technology, Chongqing Academy of Science & Technology, Chongqing 401123, ChinaTo study the relationship between antimicrobial resistance and the concentration of antibiotics, a competitive population dynamical model is proposed between the susceptible strain and the resistant strain with antibiotic exposure. The strict mathematical analysis is performed, and the results indicate that long-term high strength antibiotic treatment and prevention can induce the extinction of susceptible strain. Thus, the prescribed dose of antibiotics must be strictly controlled during the treatment and prevention of the infections in clinics.http://dx.doi.org/10.1155/2014/173952 |
| spellingShingle | Chunji Huang Aijun Fan Antimicrobial Resistance within Host: A Population Dynamics View Abstract and Applied Analysis |
| title | Antimicrobial Resistance within Host: A Population Dynamics View |
| title_full | Antimicrobial Resistance within Host: A Population Dynamics View |
| title_fullStr | Antimicrobial Resistance within Host: A Population Dynamics View |
| title_full_unstemmed | Antimicrobial Resistance within Host: A Population Dynamics View |
| title_short | Antimicrobial Resistance within Host: A Population Dynamics View |
| title_sort | antimicrobial resistance within host a population dynamics view |
| url | http://dx.doi.org/10.1155/2014/173952 |
| work_keys_str_mv | AT chunjihuang antimicrobialresistancewithinhostapopulationdynamicsview AT aijunfan antimicrobialresistancewithinhostapopulationdynamicsview |