Quercetagetin alleviates liver fibrosis in non-alcoholic fatty liver disease by promoting ferroptosis of hepatic stellate cells through GPX4 ubiquitination

Quercetagetin alleviates liver fibrosis in non-alcoholic fatty liver disease by promoting ferroptosis of hepatic stellate cells through GPX4 ubiquitination

Abstract Background Lang Qing A Ta (Huagan Tongluo Fang, HGTLF) is a Tibetan medicine with significant anti-liver fibrosis effects and good efficacy in the treatment of liver diseases, including non-alcoholic fatty liver disease (NAFLD). Quercetagetin (QG) has been identified as an active ingredient...

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Bibliographic Details
Main Authors: Yuping Qiu, Shupei Li, Mingzuo Jiang, Ang Huang, Ya Yang, Xi Chen, Hui Li, Zhizhou Yang, Juan Wei, Ji Xuan
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Chinese Medicine
Subjects:
Non-alcoholic fatty liver disease
Hepatic stellate cells
Quercetagetin
Ferroptosis
GPX4 ubiquitination
Online Access:https://doi.org/10.1186/s13020-025-01109-x
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