High-Frequency and Low-Intensity Patterned Transcranial Magnetic Stimulation over Left Dorsolateral Prefrontal Cortex as Treatment for Major Depressive Disorder: A Report of 3 Cases

Current transcranial magnetic stimulation devices apply intense (near 1 tesla) repetitive magnetic pulses over a specific area of the skull at relatively lower frequencies (1-50 Hz). Nevertheless, different studies have shown that very small magnetic fields, at higher frequencies (50-1000 Hz.), prod...

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Main Authors: Lizbeth Castillo-Aguilar, Alma E. Ríos-Ponce, Edson Albano de Mendonca, Gabriel Villafuerte
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2021/5563017
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author Lizbeth Castillo-Aguilar
Alma E. Ríos-Ponce
Edson Albano de Mendonca
Gabriel Villafuerte
author_facet Lizbeth Castillo-Aguilar
Alma E. Ríos-Ponce
Edson Albano de Mendonca
Gabriel Villafuerte
author_sort Lizbeth Castillo-Aguilar
collection DOAJ
description Current transcranial magnetic stimulation devices apply intense (near 1 tesla) repetitive magnetic pulses over a specific area of the skull at relatively lower frequencies (1-50 Hz). Nevertheless, different studies have shown that very small magnetic fields, at higher frequencies (50-1000 Hz.), produce therapeutic effects in major depressive disorder. We report the application of high-frequency and low-intensity patterned magnetic pulses over the left prefrontal dorsolateral cortex in three subjects diagnosed with clinical major depressive disorder. All three patients showed sharp changes in their self-reports as well as in the standardized clinical assessment. Hypothesized mechanisms of action of this new variant of magnetic stimulation are discussed.
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institution Kabale University
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publishDate 2021-01-01
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series Case Reports in Psychiatry
spelling doaj-art-2b278be1d31742849a8e098550bdefb42025-02-03T06:07:40ZengWileyCase Reports in Psychiatry2090-682X2090-68382021-01-01202110.1155/2021/55630175563017High-Frequency and Low-Intensity Patterned Transcranial Magnetic Stimulation over Left Dorsolateral Prefrontal Cortex as Treatment for Major Depressive Disorder: A Report of 3 CasesLizbeth Castillo-Aguilar0Alma E. Ríos-Ponce1Edson Albano de Mendonca2Gabriel Villafuerte3Clínica Coyoacán, Mexico City, MexicoClínica Coyoacán, Mexico City, MexicoHospital Psiquiátrico “Dr. Samuel Ramírez Moreno”, State of Mexico, MexicoPlan de Estudios Combinados en Medicina (PECEM), Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, MexicoCurrent transcranial magnetic stimulation devices apply intense (near 1 tesla) repetitive magnetic pulses over a specific area of the skull at relatively lower frequencies (1-50 Hz). Nevertheless, different studies have shown that very small magnetic fields, at higher frequencies (50-1000 Hz.), produce therapeutic effects in major depressive disorder. We report the application of high-frequency and low-intensity patterned magnetic pulses over the left prefrontal dorsolateral cortex in three subjects diagnosed with clinical major depressive disorder. All three patients showed sharp changes in their self-reports as well as in the standardized clinical assessment. Hypothesized mechanisms of action of this new variant of magnetic stimulation are discussed.http://dx.doi.org/10.1155/2021/5563017
spellingShingle Lizbeth Castillo-Aguilar
Alma E. Ríos-Ponce
Edson Albano de Mendonca
Gabriel Villafuerte
High-Frequency and Low-Intensity Patterned Transcranial Magnetic Stimulation over Left Dorsolateral Prefrontal Cortex as Treatment for Major Depressive Disorder: A Report of 3 Cases
Case Reports in Psychiatry
title High-Frequency and Low-Intensity Patterned Transcranial Magnetic Stimulation over Left Dorsolateral Prefrontal Cortex as Treatment for Major Depressive Disorder: A Report of 3 Cases
title_full High-Frequency and Low-Intensity Patterned Transcranial Magnetic Stimulation over Left Dorsolateral Prefrontal Cortex as Treatment for Major Depressive Disorder: A Report of 3 Cases
title_fullStr High-Frequency and Low-Intensity Patterned Transcranial Magnetic Stimulation over Left Dorsolateral Prefrontal Cortex as Treatment for Major Depressive Disorder: A Report of 3 Cases
title_full_unstemmed High-Frequency and Low-Intensity Patterned Transcranial Magnetic Stimulation over Left Dorsolateral Prefrontal Cortex as Treatment for Major Depressive Disorder: A Report of 3 Cases
title_short High-Frequency and Low-Intensity Patterned Transcranial Magnetic Stimulation over Left Dorsolateral Prefrontal Cortex as Treatment for Major Depressive Disorder: A Report of 3 Cases
title_sort high frequency and low intensity patterned transcranial magnetic stimulation over left dorsolateral prefrontal cortex as treatment for major depressive disorder a report of 3 cases
url http://dx.doi.org/10.1155/2021/5563017
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