Extended Distal Pancreatectomy with En Bloc Resection of the Celiac Axis for Locally Advanced Pancreatic Cancer: A Case Report and Review of the Literature

Due to a lack of early symptoms, pancreatic cancers of the body and tail are discovered mostly at advanced stages. These locally advanced cancers often involve the celiac axis or the common hepatic artery and are therefore declared unresectable. The extended distal pancreatectomy with en bloc resect...

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Main Authors: Patrick H. Alizai, Andreas H. Mahnken, Christian D. Klink, Ulf P. Neumann, Karsten Junge
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2012/543167
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author Patrick H. Alizai
Andreas H. Mahnken
Christian D. Klink
Ulf P. Neumann
Karsten Junge
author_facet Patrick H. Alizai
Andreas H. Mahnken
Christian D. Klink
Ulf P. Neumann
Karsten Junge
author_sort Patrick H. Alizai
collection DOAJ
description Due to a lack of early symptoms, pancreatic cancers of the body and tail are discovered mostly at advanced stages. These locally advanced cancers often involve the celiac axis or the common hepatic artery and are therefore declared unresectable. The extended distal pancreatectomy with en bloc resection of the celiac artery may offer a chance of complete resection. We present the case of a 48-year-old female with pancreatic body cancer invading the celiac axis. The patient underwent laparoscopy to exclude hepatic and peritoneal metastasis. Subsequently, a selective embolization of the common hepatic artery was performed to enlarge arterial flow to the hepatobiliary system and the stomach via the pancreatoduodenal arcades from the superior mesenteric artery. Fifteen days after embolization, the extended distal pancreatectomy with splenectomy and en bloc resection of the celiac axis was carried out. The postoperative course was uneventful, and complete tumor resection was achieved. This case report and a review of the literature show the feasibility and safety of the extended distal pancreatectomy with en bloc resection of the celiac axis. A preoperative embolization of the celiac axis may avoid ischemia-related complications of the stomach or the liver.
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spelling doaj-art-2af8e99a69024736ac882bb36525bb772025-02-03T06:08:15ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/543167543167Extended Distal Pancreatectomy with En Bloc Resection of the Celiac Axis for Locally Advanced Pancreatic Cancer: A Case Report and Review of the LiteraturePatrick H. Alizai0Andreas H. Mahnken1Christian D. Klink2Ulf P. Neumann3Karsten Junge4Department of General, Visceral and Transplantat Surgery, University Hospital of the RWTH Aachen, Pauwelsstr 30, 52074 Aachen, GermanyDepartment of Diagnostic and Interventional Radiology, University Hospital of the RWTH Aachen, Pauwelsstr 30, 52074 Aachen, GermanyDepartment of General, Visceral and Transplantat Surgery, University Hospital of the RWTH Aachen, Pauwelsstr 30, 52074 Aachen, GermanyDepartment of General, Visceral and Transplantat Surgery, University Hospital of the RWTH Aachen, Pauwelsstr 30, 52074 Aachen, GermanyDepartment of General, Visceral and Transplantat Surgery, University Hospital of the RWTH Aachen, Pauwelsstr 30, 52074 Aachen, GermanyDue to a lack of early symptoms, pancreatic cancers of the body and tail are discovered mostly at advanced stages. These locally advanced cancers often involve the celiac axis or the common hepatic artery and are therefore declared unresectable. The extended distal pancreatectomy with en bloc resection of the celiac artery may offer a chance of complete resection. We present the case of a 48-year-old female with pancreatic body cancer invading the celiac axis. The patient underwent laparoscopy to exclude hepatic and peritoneal metastasis. Subsequently, a selective embolization of the common hepatic artery was performed to enlarge arterial flow to the hepatobiliary system and the stomach via the pancreatoduodenal arcades from the superior mesenteric artery. Fifteen days after embolization, the extended distal pancreatectomy with splenectomy and en bloc resection of the celiac axis was carried out. The postoperative course was uneventful, and complete tumor resection was achieved. This case report and a review of the literature show the feasibility and safety of the extended distal pancreatectomy with en bloc resection of the celiac axis. A preoperative embolization of the celiac axis may avoid ischemia-related complications of the stomach or the liver.http://dx.doi.org/10.1155/2012/543167
spellingShingle Patrick H. Alizai
Andreas H. Mahnken
Christian D. Klink
Ulf P. Neumann
Karsten Junge
Extended Distal Pancreatectomy with En Bloc Resection of the Celiac Axis for Locally Advanced Pancreatic Cancer: A Case Report and Review of the Literature
Case Reports in Medicine
title Extended Distal Pancreatectomy with En Bloc Resection of the Celiac Axis for Locally Advanced Pancreatic Cancer: A Case Report and Review of the Literature
title_full Extended Distal Pancreatectomy with En Bloc Resection of the Celiac Axis for Locally Advanced Pancreatic Cancer: A Case Report and Review of the Literature
title_fullStr Extended Distal Pancreatectomy with En Bloc Resection of the Celiac Axis for Locally Advanced Pancreatic Cancer: A Case Report and Review of the Literature
title_full_unstemmed Extended Distal Pancreatectomy with En Bloc Resection of the Celiac Axis for Locally Advanced Pancreatic Cancer: A Case Report and Review of the Literature
title_short Extended Distal Pancreatectomy with En Bloc Resection of the Celiac Axis for Locally Advanced Pancreatic Cancer: A Case Report and Review of the Literature
title_sort extended distal pancreatectomy with en bloc resection of the celiac axis for locally advanced pancreatic cancer a case report and review of the literature
url http://dx.doi.org/10.1155/2012/543167
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