Recent Nanotechnological Trends in the Management of Microbial Keratitis
Microbial keratitis (MK) is a sight-threatening ocular disease that needs rapid diagnosis and treatment to prevent more serious outcomes. The broad-spectrum topical antimicrobial treatment is currently the main pharmacological approach for MK management, yet its efficacy is increasingly challenged...
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| Format: | Article |
| Language: | English |
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Knowledge E
2024-12-01
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| Series: | Journal of Ophthalmic & Vision Research |
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| Online Access: | https://knepublishing.com/index.php/JOVR/article/view/14498 |
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| author | Shraddha Jaiswal Prabhavati Shinde Vidya Tale |
| author_facet | Shraddha Jaiswal Prabhavati Shinde Vidya Tale |
| author_sort | Shraddha Jaiswal |
| collection | DOAJ |
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Microbial keratitis (MK) is a sight-threatening ocular disease that needs rapid diagnosis and treatment to prevent more serious outcomes. The broad-spectrum topical antimicrobial treatment is currently the main pharmacological approach for MK management, yet its efficacy is increasingly challenged by evolving antimicrobial resistance, including multidrug resistance. Also, the ocular surface presents numerous challenges for standard topical drug delivery. The failure and ineffectiveness of current therapies have necessitated the development of novel therapeutic strategies to manage MK. With advances in nanotechnology in the biomedical field, various nanomaterials can be employed to control MK. The primary determinants of nanoparticles’ vast range of applications are their size, surface properties, and chemical makeup, which also happen to be the same elements that give rise to their poisonous and dangerous effects. In this study, we provide a perspective on the contact lens-associated corneal illnesses such as MK and explore how nanotechnology might help address this significant clinical issue. In addition, safety and toxicological concerns about the increasingly widespread use of contact lenses are also discussed.
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| format | Article |
| id | doaj-art-2af57c463d854cc29e9f1a729406abb8 |
| institution | Kabale University |
| issn | 2008-2010 2008-322X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Knowledge E |
| record_format | Article |
| series | Journal of Ophthalmic & Vision Research |
| spelling | doaj-art-2af57c463d854cc29e9f1a729406abb82025-01-21T05:15:07ZengKnowledge EJournal of Ophthalmic & Vision Research2008-20102008-322X2024-12-0119410.18502/jovr.v19i4.14498Recent Nanotechnological Trends in the Management of Microbial KeratitisShraddha Jaiswal0Prabhavati Shinde 1Vidya Tale2Rajiv Gandhi Institute of IT And Biotechnology, Bharati Vidyapeeth Deemed to be University, Pune, IndiaRajiv Gandhi Institute of IT And Biotechnology, Bharati Vidyapeeth Deemed to be University, Pune, IndiaRajiv Gandhi Institute of IT And Biotechnology, Bharati Vidyapeeth Deemed to be University, Pune, India Microbial keratitis (MK) is a sight-threatening ocular disease that needs rapid diagnosis and treatment to prevent more serious outcomes. The broad-spectrum topical antimicrobial treatment is currently the main pharmacological approach for MK management, yet its efficacy is increasingly challenged by evolving antimicrobial resistance, including multidrug resistance. Also, the ocular surface presents numerous challenges for standard topical drug delivery. The failure and ineffectiveness of current therapies have necessitated the development of novel therapeutic strategies to manage MK. With advances in nanotechnology in the biomedical field, various nanomaterials can be employed to control MK. The primary determinants of nanoparticles’ vast range of applications are their size, surface properties, and chemical makeup, which also happen to be the same elements that give rise to their poisonous and dangerous effects. In this study, we provide a perspective on the contact lens-associated corneal illnesses such as MK and explore how nanotechnology might help address this significant clinical issue. In addition, safety and toxicological concerns about the increasingly widespread use of contact lenses are also discussed. https://knepublishing.com/index.php/JOVR/article/view/14498Antimicrobial ResistanceContact LensesCorneal DiseasesMicrobial KeratitisNanotechnology |
| spellingShingle | Shraddha Jaiswal Prabhavati Shinde Vidya Tale Recent Nanotechnological Trends in the Management of Microbial Keratitis Journal of Ophthalmic & Vision Research Antimicrobial Resistance Contact Lenses Corneal Diseases Microbial Keratitis Nanotechnology |
| title | Recent Nanotechnological Trends in the Management of Microbial Keratitis |
| title_full | Recent Nanotechnological Trends in the Management of Microbial Keratitis |
| title_fullStr | Recent Nanotechnological Trends in the Management of Microbial Keratitis |
| title_full_unstemmed | Recent Nanotechnological Trends in the Management of Microbial Keratitis |
| title_short | Recent Nanotechnological Trends in the Management of Microbial Keratitis |
| title_sort | recent nanotechnological trends in the management of microbial keratitis |
| topic | Antimicrobial Resistance Contact Lenses Corneal Diseases Microbial Keratitis Nanotechnology |
| url | https://knepublishing.com/index.php/JOVR/article/view/14498 |
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