Long Noncoding RNAs in Metabolic Syndrome Related Disorders

Ribonucleic acids (RNAs) are very complex and their all functions have yet to be fully clarified. Noncoding genes (noncoding RNA, sequences, and pseudogenes) comprise 67% of all genes and they are represented by housekeeping noncoding RNAs (transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RN...

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Main Authors: Magdalena Losko, Jerzy Kotlinowski, Jolanta Jura
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2016/5365209
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author Magdalena Losko
Jerzy Kotlinowski
Jolanta Jura
author_facet Magdalena Losko
Jerzy Kotlinowski
Jolanta Jura
author_sort Magdalena Losko
collection DOAJ
description Ribonucleic acids (RNAs) are very complex and their all functions have yet to be fully clarified. Noncoding genes (noncoding RNA, sequences, and pseudogenes) comprise 67% of all genes and they are represented by housekeeping noncoding RNAs (transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RNA (snRNA), and small nucleolar RNA (snoRNA)) that are engaged in basic cellular processes and by regulatory noncoding RNA (short and long noncoding RNA (ncRNA)) that are important for gene expression/transcript stability. In this review, we summarize data concerning the significance of long noncoding RNAs (lncRNAs) in metabolic syndrome related disorders, focusing on adipose tissue and pancreatic islands.
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series Mediators of Inflammation
spelling doaj-art-2ad4e388940d42d2a608ab7bfea5dcca2025-02-03T01:33:28ZengWileyMediators of Inflammation0962-93511466-18612016-01-01201610.1155/2016/53652095365209Long Noncoding RNAs in Metabolic Syndrome Related DisordersMagdalena Losko0Jerzy Kotlinowski1Jolanta Jura2Faculty of Biochemistry, Biophysics and Biotechnology, Department of General Biochemistry, Jagiellonian University, Krakow, PolandFaculty of Biochemistry, Biophysics and Biotechnology, Department of General Biochemistry, Jagiellonian University, Krakow, PolandFaculty of Biochemistry, Biophysics and Biotechnology, Department of General Biochemistry, Jagiellonian University, Krakow, PolandRibonucleic acids (RNAs) are very complex and their all functions have yet to be fully clarified. Noncoding genes (noncoding RNA, sequences, and pseudogenes) comprise 67% of all genes and they are represented by housekeeping noncoding RNAs (transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RNA (snRNA), and small nucleolar RNA (snoRNA)) that are engaged in basic cellular processes and by regulatory noncoding RNA (short and long noncoding RNA (ncRNA)) that are important for gene expression/transcript stability. In this review, we summarize data concerning the significance of long noncoding RNAs (lncRNAs) in metabolic syndrome related disorders, focusing on adipose tissue and pancreatic islands.http://dx.doi.org/10.1155/2016/5365209
spellingShingle Magdalena Losko
Jerzy Kotlinowski
Jolanta Jura
Long Noncoding RNAs in Metabolic Syndrome Related Disorders
Mediators of Inflammation
title Long Noncoding RNAs in Metabolic Syndrome Related Disorders
title_full Long Noncoding RNAs in Metabolic Syndrome Related Disorders
title_fullStr Long Noncoding RNAs in Metabolic Syndrome Related Disorders
title_full_unstemmed Long Noncoding RNAs in Metabolic Syndrome Related Disorders
title_short Long Noncoding RNAs in Metabolic Syndrome Related Disorders
title_sort long noncoding rnas in metabolic syndrome related disorders
url http://dx.doi.org/10.1155/2016/5365209
work_keys_str_mv AT magdalenalosko longnoncodingrnasinmetabolicsyndromerelateddisorders
AT jerzykotlinowski longnoncodingrnasinmetabolicsyndromerelateddisorders
AT jolantajura longnoncodingrnasinmetabolicsyndromerelateddisorders