Long Noncoding RNAs in Metabolic Syndrome Related Disorders
Ribonucleic acids (RNAs) are very complex and their all functions have yet to be fully clarified. Noncoding genes (noncoding RNA, sequences, and pseudogenes) comprise 67% of all genes and they are represented by housekeeping noncoding RNAs (transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RN...
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Format: | Article |
Language: | English |
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Wiley
2016-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2016/5365209 |
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author | Magdalena Losko Jerzy Kotlinowski Jolanta Jura |
author_facet | Magdalena Losko Jerzy Kotlinowski Jolanta Jura |
author_sort | Magdalena Losko |
collection | DOAJ |
description | Ribonucleic acids (RNAs) are very complex and their all functions have yet to be fully clarified. Noncoding genes (noncoding RNA, sequences, and pseudogenes) comprise 67% of all genes and they are represented by housekeeping noncoding RNAs (transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RNA (snRNA), and small nucleolar RNA (snoRNA)) that are engaged in basic cellular processes and by regulatory noncoding RNA (short and long noncoding RNA (ncRNA)) that are important for gene expression/transcript stability. In this review, we summarize data concerning the significance of long noncoding RNAs (lncRNAs) in metabolic syndrome related disorders, focusing on adipose tissue and pancreatic islands. |
format | Article |
id | doaj-art-2ad4e388940d42d2a608ab7bfea5dcca |
institution | Kabale University |
issn | 0962-9351 1466-1861 |
language | English |
publishDate | 2016-01-01 |
publisher | Wiley |
record_format | Article |
series | Mediators of Inflammation |
spelling | doaj-art-2ad4e388940d42d2a608ab7bfea5dcca2025-02-03T01:33:28ZengWileyMediators of Inflammation0962-93511466-18612016-01-01201610.1155/2016/53652095365209Long Noncoding RNAs in Metabolic Syndrome Related DisordersMagdalena Losko0Jerzy Kotlinowski1Jolanta Jura2Faculty of Biochemistry, Biophysics and Biotechnology, Department of General Biochemistry, Jagiellonian University, Krakow, PolandFaculty of Biochemistry, Biophysics and Biotechnology, Department of General Biochemistry, Jagiellonian University, Krakow, PolandFaculty of Biochemistry, Biophysics and Biotechnology, Department of General Biochemistry, Jagiellonian University, Krakow, PolandRibonucleic acids (RNAs) are very complex and their all functions have yet to be fully clarified. Noncoding genes (noncoding RNA, sequences, and pseudogenes) comprise 67% of all genes and they are represented by housekeeping noncoding RNAs (transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RNA (snRNA), and small nucleolar RNA (snoRNA)) that are engaged in basic cellular processes and by regulatory noncoding RNA (short and long noncoding RNA (ncRNA)) that are important for gene expression/transcript stability. In this review, we summarize data concerning the significance of long noncoding RNAs (lncRNAs) in metabolic syndrome related disorders, focusing on adipose tissue and pancreatic islands.http://dx.doi.org/10.1155/2016/5365209 |
spellingShingle | Magdalena Losko Jerzy Kotlinowski Jolanta Jura Long Noncoding RNAs in Metabolic Syndrome Related Disorders Mediators of Inflammation |
title | Long Noncoding RNAs in Metabolic Syndrome Related Disorders |
title_full | Long Noncoding RNAs in Metabolic Syndrome Related Disorders |
title_fullStr | Long Noncoding RNAs in Metabolic Syndrome Related Disorders |
title_full_unstemmed | Long Noncoding RNAs in Metabolic Syndrome Related Disorders |
title_short | Long Noncoding RNAs in Metabolic Syndrome Related Disorders |
title_sort | long noncoding rnas in metabolic syndrome related disorders |
url | http://dx.doi.org/10.1155/2016/5365209 |
work_keys_str_mv | AT magdalenalosko longnoncodingrnasinmetabolicsyndromerelateddisorders AT jerzykotlinowski longnoncodingrnasinmetabolicsyndromerelateddisorders AT jolantajura longnoncodingrnasinmetabolicsyndromerelateddisorders |