Altered zygotic gene expression caused by sperm with Tdrd6 variants disrupts early embryonic development

Altered zygotic gene expression caused by sperm with Tdrd6 variants disrupts early embryonic development

Abstract The precise mechanisms behind early embryonic arrest due to sperm‐related factors and the most effective strategies are not yet fully understood. Here, we present two cases of male infertility linked to novel TDRD6 variants, associated with oligoasthenoteratozoospermia (OAT) and early embry...

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Main Authors: Zhijie Hu, Yuqi Zhang, Renfei Cai, Qiuju Chen, Haiyan Guo, Danjun Li, Weidong Lin, Hongxi He, Haibo Wu, Yali Liu, Bin Li, Qianwen Xi, Hongyuan Gao, Jian Zhang, Qifeng Lyu, Yanping Kuang, Xuefeng Lu
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:MedComm
Subjects:
artificial oocyte activation
assisted reproductive technology
early embryonic arrest
infertility
TDRD6
Online Access:https://doi.org/10.1002/mco2.70038
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https://doi.org/10.1002/mco2.70038

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